Ebola viruses are the causative agents of a severe form of viral haemorrhagic fever in man,
designated Ebola haemorrhagic fever, and are endemic in regions of central Africa. The …

Ebola and Marburg hemorrhagic fevers (EHF and MHF) are caused by the Filoviridae family,
Ebolavirus and Marburgvirus (ebolavirus and marburgvirus), respectively. These severe …

Filovirus infections can cause a severe and often fatal disease in humans and nonhuman
primates, including great apes. Here, three anti-Ebola virus mouse/human chimeric mAbs …

Background We previously showed that small interfering RNAs (siRNAs) targeting the Zaire
Ebola virus (ZEBOV) RNA polymerase L protein formulated in stable nucleic acid-lipid …

Ebola virus (EBOV) remains one of the most lethal transmissible infections and is
responsible for high fatality rates and substantial morbidity during sporadic outbreaks. With …

The mortality, morbidity, and disease diversity of tuberculosis varies substantially between
different age groups (figure). 1–4 These differences need clarifying because a better …

Currently, no vaccines or therapeutics are licensed to counter Ebola or Marburg viruses,
highly pathogenic filoviruses that are causative agents of viral hemorrhagic fever. Here we …

The filoviruses—Ebola virus and Marburg virus—cause lethal haemorrhagic fever in
humans and non-human primates (NHPs). Filoviruses present a global health threat both as …

The highly pathogenic filoviruses, Marburg and Ebola virus, belong to the nonsegmented
negative-sense RNA viruses of the order Mononegavirales. The mode of replication and …

Ebola and Marburg viruses are the only members of the Filoviridae family (order
Mononegavirales), a group of viruses characterized by a linear, non-segmented, single …