Bone regeneration is a complex process that is influenced by tissue interactions,
inflammatory responses, and progenitor cells. Diseases, lifestyle, or multiple trauma can …

Osteoarthritis (OA) is an age related joint disease associated with degeneration and loss of
articular cartilage. Consequently, OA patients suffer from chronic joint pain and disability …

Vimentin is one of the first cytoplasmic intermediate filaments to be expressed in mammalian
cells during embryogenesis, but its role in cellular fitness has long been a mystery. Vimentin …

Continued improvements in the understanding and application of mesenchymal stem cells
(MSC) have revolutionized tissue engineering. This is particularly true within the field of …

Cell repair/replacing strategies for neurodegenerative diseases such as Parkinson's disease
depend on well-characterized dopaminergic neuronal candidates that are healthy and show …

Type 1 diabetes mellitus (T1DM) is an autoimmune condition that results in the destruction of
insulin-secreting β cells of the islets of Langerhans. Allogeneic islet transplantation could be …

Spinal cord injury (SCI) is a devastating condition that can result in lifelong disability.
Despite significant progress in SCI research, current treatments only offer limited functional …

Introduction: Dialysis and renal transplantation are the only two therapeutic options offered
to patients affected by end-stage kidney disease; however, neither treatment can be …

Basic science and experimental research on stem cells has increased exponentially in the
last decade. Our present knowledge about stem cell biology is better than ever before. This …

Bone/fracture healing is a complex process with different steps and four basic tissue layers
being affected: cortical bone, periosteum, fascial tissue surrounding the fracture, and bone …