Pulmonary sarcomatoid carcinoma: progress, treatment and expectations

X Li, D Wu, H Liu, J Chen - Therapeutic Advances in …, 2020 - journals.sagepub.com
Pulmonary sarcomatoid carcinoma (PSC) is a unique, highly invasive pulmonary
malignancy with a poor prognosis, representing 0.1–0.4% of all malignant lung tumors …

Approaches to tumor classification in pulmonary sarcomatoid carcinoma

C Baldovini, G Rossi, A Ciarrocchi - Lung Cancer: Targets and …, 2019 - Taylor & Francis
Pulmonary sarcomatoid carcinoma (PSC) is a heterogeneous category of primary lung
cancer accounting from 0.3% to 3% of all primary lung malignancies. According to the most …

Integrated molecular characterization reveals potential therapeutic strategies for pulmonary sarcomatoid carcinoma

Z Yang, J Xu, L Li, R Li, Y Wang, Y Tian, W Guo… - Nature …, 2020 - nature.com
Pulmonary sarcomatoid carcinoma (PSC) is a rare subtype of lung cancer with poor
prognosis. Here, we perform multi-omics analysis of 56 PSC samples, 14 of which are …

Immunophenotyping of pulmonary sarcomatoid carcinoma

Y Ma, W Li, Z Li, J Chen, H Wang, T Jiang… - Frontiers in …, 2022 - frontiersin.org
Background Previous studies have suggested that patients with pulmonary sarcomatoid
carcinoma (PSC) may benefit from immune checkpoint inhibitors (ICIs); however, relevant …

Genomic origin and intratumor heterogeneity revealed by sequencing on carcinomatous and sarcomatous components of pulmonary sarcomatoid carcinoma

X Liu, F Wang, C Xu, X Chen, X Hou, Q Li, P Li, Z Xie… - Oncogene, 2021 - nature.com
Pulmonary sarcomatoid carcinoma (PSC) contains carcinomatous component (CaC) and
sarcomatous component (SaC). Herein, we explored the genomic origin and intratumor …

Multimodality treatment of pulmonary sarcomatoid carcinoma: a review of current state of art

L Zhang, W Lin, Z Yang, R Li, Y Gao… - Journal of Oncology, 2022 - Wiley Online Library
Pulmonary sarcomatoid carcinoma (PSC) is an unconventional non‐small‐cell lung cancer
(NSCLC) that is currently managed under guidelines used for conventional NSCLC and has …

[HTML][HTML] Specific genomic alterations and prognostic analysis of perihilar cholangiocarcinoma and distal cholangiocarcinoma

Y Zheng, Y Qin, W Gong, H Li, B Li… - Journal of …, 2021 - ncbi.nlm.nih.gov
Background Cholangiocarcinoma (CCA), which consists of intrahepatic CCA (iCCA),
perihilar CCA (pCCA), and distal CCA (dCCA), is an aggressive malignancy worldwide …

[HTML][HTML] Adjuvant chemotherapy for pulmonary sarcomatoid carcinoma: A retrospective analysis of the National Cancer Database

HM Abdallah, D Martinez-Meehan, W Lutfi… - The Journal of Thoracic …, 2022 - Elsevier
Objectives Pulmonary sarcomatoid carcinoma (PSC) is a rarely occurring variant of non-
small cell lung cancer with sarcoma-like features. Compared with traditional non-small cell …

Pten and p53 loss in the mouse lung causes adenocarcinoma and sarcomatoid carcinoma

S Lázaro, C Lorz, AB Enguita, I Seller, JM Paramio… - Cancers, 2022 - mdpi.com
Simple Summary Lung cancer is the world leading cause of cancer death. Therefore, a
better understanding of the disease is needed to improve patient survival. In this work, we …

Genomic characterization of undifferentiated sarcomatoid carcinoma of the pancreas

A Gkountakos, A Mafficini, E Lou, G Malleo, R Salvia… - Human pathology, 2022 - Elsevier
Undifferentiated sarcomatoid carcinoma (USC) of the pancreas is a rare but especially
aggressive variant of pancreatic ductal adenocarcinoma (PDAC), composed of at least 80 …