We have known for many years that estrogen is more than the female hormone. It is
essential in the male gonads, and in both sexes, estrogen has functions in the skeleton and …

Little is known about the pathophysiology of pelvic organ prolapse (POP). In 1996, Jackson
presented a hypothesis on pelvic floor connective tissue that tried to explain the …

Objective: The aim of this study is to confirm the local beneficial effects of intravaginal
dehydroepiandrosterone (DHEA, Prasterone) on moderate to severe dyspareunia or pain at …

Unlike hot flushes and night sweats which resolve spontaneously in time, atrophic symptoms
affecting the vagina and lower urinary tract are often progressive and frequently require …

Pelvic floor disorders such as pelvic organ prolapse, urinary incontinence, and fecal
incontinence affect a large number of women each year. The pelvic floor can be thought of …

OBJECTIVE: As pelvic organ prolapse progresses, the morphology of the vagina
dramatically changes. The objective of this study was to determine whether these changes …

The pelvic floor (PF) is made of muscles, ligaments, and fascia, which ensure organ statics,
maintain muscle tone, and are involved in contractions. This review describes the myofascial …

Achilles tendinopathy is a degenerative, not an inflammatory, condition. It is prevalent in
athletes involved in running sports. A systematic literature review on Achilles tendon …

In humans, structural and functional changes attributable to aging are more visibly evident in
the skin than in any other organ. Estrogens have significant effects on skin physiology and …

Objectives: A significant body of knowledge implicates menopausal estrogen levels in the
pathogenesis of the common pelvic floor disorders (PFDs). These health conditions …