AIM To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs)
therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a …

Preventing Gastrointestinal Bleeding in the Hospital Acid suppression is widely used to
lower the risk of gastrointestinal bleeding in critically ill patients, and the practice has spread …

Purpose To analyse the prevalence of long‐term use of proton pump inhibitors (PPI) with
respect to underlying diseases and drugs, and to find predictors for such treatment when an …

Clostridium difficile is a Gram-positive obligate anaerobe that forms spores in order to
survive for long periods in the unfavorable environment outside a host. C. difficile is the …

Background A large proportion of proton pump inhibitor (PPI) prescriptions, including those
for stress ulcer prophylaxis (SUP), are inappropriate. Our study purpose was to …

Introduction Proton pump inhibitor (PPI) prescriptions have raised concern for both huge
increase of health expenditure and possible long-term adverse effects. Objective To …

Background: Proton pump inhibitors (PPIs) are effective medications for acid-related
disorders; however, they are also overused and may be associated with several adverse …

Proton pump inhibitors (PPIs) are the most effective gastric acid-suppressing agents and the
mainstay medical therapy for a series of acid peptic diseases. In general, the safety profile of …

Background The prescriptions of proton pump inhibitors (PPIs) have been widely concerned
due to both huge increase in medical costs and possible long-term adverse events (AEs) …

Background There is a lack of specific data about the efficacy and safety of medications
administered via feeding tubes, although there is a general awareness that not all drug …