Molecular bases of VEGFR-2-mediated physiological function and pathological role
X Wang, AM Bove, G Simone, B Ma - Frontiers in Cell and …, 2020 - frontiersin.org
The vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) play crucial
roles in vasculogenesis and angiogenesis. Angiogenesis is an important mechanism in …
roles in vasculogenesis and angiogenesis. Angiogenesis is an important mechanism in …
[HTML][HTML] Vascular endothelial growth factor receptor (VEGFR-2)/KDR inhibitors: medicinal chemistry perspective
SJ Modi, VM Kulkarni - Medicine in Drug Discovery, 2019 - Elsevier
New blood vessels formation from the existing vasculature is called angiogenesis. It is an
essential physiological process for the growth of cells, tissue repair, wound healing, and …
essential physiological process for the growth of cells, tissue repair, wound healing, and …
Signal transduction by vascular endothelial growth factor receptors
S Koch, L Claesson-Welsh - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Vascular endothelial growth factors (VEGFs) are master regulators of vascular development
and of blood and lymphatic vessel function during health and disease in the adult. It is …
and of blood and lymphatic vessel function during health and disease in the adult. It is …
Signal transduction by vascular endothelial growth factor receptors
S Koch, S Tugues, X Li, L Gualandi… - Biochemical …, 2011 - portlandpress.com
VEGFs (vascular endothelial growth factors) control vascular development during
embryogenesis and the function of blood vessels and lymphatic vessels in the adult. There …
embryogenesis and the function of blood vessels and lymphatic vessels in the adult. There …
VEGF receptor signalling? In control of vascular function
AK Olsson, A Dimberg, J Kreuger… - … reviews Molecular cell …, 2006 - nature.com
Vascular endothelial growth-factor receptors (VEGFRs) regulate the cardiovascular system.
VEGFR1 is required for the recruitment of haematopoietic precursors and migration of …
VEGFR1 is required for the recruitment of haematopoietic precursors and migration of …
Endothelial cell migration during angiogenesis
Endothelial cell migration is essential to angiogenesis. This motile process is directionally
regulated by chemotactic, haptotactic, and mechanotactic stimuli and further involves …
regulated by chemotactic, haptotactic, and mechanotactic stimuli and further involves …
Vascular endothelial growth factor receptor-2: structure, function, intracellular signalling and therapeutic inhibition
K Holmes, OL Roberts, AM Thomas, MJ Cross - Cellular signalling, 2007 - Elsevier
Vascular endothelial growth factors (VEGFs) regulate vascular development, angiogenesis
and lymphangiogenesis by binding to a number of receptors. VEGFR-1 is required for the …
and lymphangiogenesis by binding to a number of receptors. VEGFR-1 is required for the …
The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions
H Takahashi, M Shibuya - Clinical science, 2005 - portlandpress.com
The VEGF (vascular endothelial growth factor) family and its receptors are essential
regulators of angiogenesis and vascular permeability. Currently, the VEGF family consists of …
regulators of angiogenesis and vascular permeability. Currently, the VEGF family consists of …
Vascular endothelial growth factor in eye disease
Collectively, angiogenic ocular conditions represent the leading cause of irreversible vision
loss in developed countries. In the US, for example, retinopathy of prematurity, diabetic …
loss in developed countries. In the US, for example, retinopathy of prematurity, diabetic …
VEGF controls endothelial-cell permeability by promoting the β-arrestin-dependent endocytosis of VE-cadherin
J Gavard, JS Gutkind - Nature cell biology, 2006 - nature.com
How vascular endothelial growth factor (VEGF) induces vascular permeability, its first
described function, remains poorly understood. Here, we provide evidence of a novel …
described function, remains poorly understood. Here, we provide evidence of a novel …