Utilizing the sublingual form of squalene in COVID-19 patients: a randomized clinical trial
In this study, the efficacy of sublingual squalene in decreasing the mortality rate among
patients with COVID-19 was investigated. Squalene was extracted from pumpkin seed oil …
patients with COVID-19 was investigated. Squalene was extracted from pumpkin seed oil …
Immunological study of COVID-19 vaccine candidate based on recombinant spike trimer protein from different SARS-CoV-2 variants of concern
E Rudi, P Martin Aispuro, E Zurita… - Frontiers in …, 2022 - frontiersin.org
The emergency of new SARS-CoV-2 variants that feature increased immune escape marks
an urgent demand for better vaccines that will provide broader immunogenicity. Here, we …
an urgent demand for better vaccines that will provide broader immunogenicity. Here, we …
Immunogenicity and safety of adjuvant-associated COVID-19 vaccines: A systematic review and meta-analysis of randomized controlled trials
MQ Cheng, R Li, X Luo, JY Chen, ZP Bai, P Zhao… - Heliyon, 2023 - cell.com
Background The benefits and risks of adjuvant-associated COVID-19 vaccines (ACVs) are
unclear. The study aimed to assess the immunogenicity and safety of ACVs compared with …
unclear. The study aimed to assess the immunogenicity and safety of ACVs compared with …
Improved expression of SARS-CoV-2 spike RBD using the insect cell-baculovirus system
J Poodts, I Smith, JM Birenbaum, MS Rodriguez… - Viruses, 2022 - mdpi.com
Insect cell-baculovirus expression vector system is one of the most established platforms to
produce biological products, and it plays a fundamental role in the context of COVID-19 …
produce biological products, and it plays a fundamental role in the context of COVID-19 …
Quality attributes of CTVad1, a nanoemulsified adjuvant for phase I clinical trial of SpiN COVID-19 vaccine
BR Dias Assis, IP Gomes, JT de Castro, GG Rivelli… - …, 2023 - Taylor & Francis
Aim: To develop, characterize and evaluate an oil/water nanoemulsion with squalene
(CTVad1) to be approved as an adjuvant for the SpiN COVID-19 vaccine clinical trials …
(CTVad1) to be approved as an adjuvant for the SpiN COVID-19 vaccine clinical trials …
Stability of shark (Centrophorus sp.) liver oil rich in squalene as an immunostimulant
Shark liver oil has been widely produced in Indonesia; however, many shark liver oil
products still do not meet the established standards. This research involves the addition of …
products still do not meet the established standards. This research involves the addition of …