Harnessing monocyte‐derived macrophages to control central nervous system pathologies: no longer 'if'but 'how'
R Shechter, M Schwartz - The Journal of pathology, 2013 - Wiley Online Library
The central nervous system (CNS) tissues, including the brain, the eye, and the spinal cord,
are immune‐privileged, secluded from the circulation by a complex of barriers, and …
are immune‐privileged, secluded from the circulation by a complex of barriers, and …
Breaching brain barriers: B cell migration in multiple sclerosis
C Rodriguez-Mogeda, S Rodríguez-Lorenzo, J Attia… - Biomolecules, 2022 - mdpi.com
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS)
known for the manifestation of demyelinated lesions throughout the CNS, leading to …
known for the manifestation of demyelinated lesions throughout the CNS, leading to …
Myeloid microvesicles are a marker and therapeutic target for neuroinflammation
C Verderio, L Muzio, E Turola, A Bergami… - Annals of …, 2012 - Wiley Online Library
Abstract Objective: Microvesicles (MVs) have been indicated as important mediators of
intercellular communication and are emerging as new biomarkers of tissue damage. Our …
intercellular communication and are emerging as new biomarkers of tissue damage. Our …
Neural precursor cells tune striatal connectivity through the release of IGFBPL1
E Butti, S Cattaneo, M Bacigaluppi… - Nature …, 2022 - nature.com
The adult brain retains over life endogenous neural stem/precursor cells (eNPCs) within the
subventricular zone (SVZ). Whether or not these cells exert physiological functions is still …
subventricular zone (SVZ). Whether or not these cells exert physiological functions is still …
Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of amyotrophic lateral sclerosis
C Rossi, M Cusimano, M Zambito, A Finardi… - Cell death & …, 2018 - nature.com
Microglia activation is a commonly pathological hallmark of neurodegenerative diseases,
such as amyotrophic lateral sclerosis (ALS), a devastating disorder characterized by a …
such as amyotrophic lateral sclerosis (ALS), a devastating disorder characterized by a …
[HTML][HTML] Inflammation-induced subventricular zone dysfunction leads to olfactory deficits in a targeted mouse model of multiple sclerosis
V Tepavčević, F Lazarini… - The Journal of …, 2011 - Am Soc Clin Investig
Neural stem cells (NSCs) persist in defined brain niches, including the subventricular zone
(SVZ), throughout adulthood and generate new neurons destined to support specific …
(SVZ), throughout adulthood and generate new neurons destined to support specific …
Impaired striatal GABA transmission in experimental autoimmune encephalomyelitis
S Rossi, L Muzio, V De Chiara, G Grasselli… - Brain, behavior, and …, 2011 - Elsevier
Synaptic dysfunction triggers neuronal damage in experimental autoimmune
encephalomyelitis (EAE), a model of multiple sclerosis (MS). While excessive glutamate …
encephalomyelitis (EAE), a model of multiple sclerosis (MS). While excessive glutamate …
The ins and outs of B cells in multiple sclerosis
K Blauth, GP Owens, JL Bennett - Frontiers in immunology, 2015 - frontiersin.org
B cells play a central role in multiple sclerosis (MS) pathology. B and plasma cells may
contribute to disease activity through multiple mechanisms: antigen presentation, cytokine …
contribute to disease activity through multiple mechanisms: antigen presentation, cytokine …
A comprehensive review on the role of chemokines in the pathogenesis of multiple sclerosis
S Ghafouri-Fard, K Honarmand, M Taheri - Metabolic Brain Disease, 2021 - Springer
Multiple sclerosis (MS) as a chronic inflammatory disorder of the central nervous system
(CNS) is thought to be caused by the abnormal induction of immune responses …
(CNS) is thought to be caused by the abnormal induction of immune responses …
Neurogenin 2 regulates progenitor cell-cycle progression and Purkinje cell dendritogenesis in cerebellar development
M Florio, K Leto, L Muzio, A Tinterri… - …, 2012 - journals.biologists.com
By serving as the sole output of the cerebellar cortex, integrating a myriad of afferent stimuli,
Purkinje cells (PCs) constitute the principal neuron in cerebellar circuits. Several …
Purkinje cells (PCs) constitute the principal neuron in cerebellar circuits. Several …