Diagnosis and Evaluation of Hypertrophic Cardiomyopathy: JACC State-of-the-Art Review

BJ Maron, MY Desai, RA Nishimura, P Spirito… - Journal of the American …, 2022 - jacc.org
Hypertrophic cardiomyopathy (HCM) is a relatively common often inherited global heart
disease, with complex phenotypic and genetic expression and natural history, affecting both …

2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: a report of the American College of Cardiology/American …

SR Ommen, S Mital, MA Burke, SM Day… - Journal of the American …, 2020 - jacc.org
The recommendations listed in this guideline are, whenever possible, evidence based. An
initial extensive evidence review, which included literature derived from research involving …

2020 ACC/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Joint …

Writing Committee Members, CM Otto… - Journal of the American …, 2021 - jacc.org
The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through March 1, 2020. Searches …

2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: executive summary: a report of the American College of …

SR Ommen, S Mital, MA Burke, SM Day… - Journal of the American …, 2020 - jacc.org
Aim This executive summary of the hypertrophic cardiomyopathy clinical practice guideline
provides recommendations and algorithms for clinicians to diagnose and manage …

Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial

I Olivotto, A Oreziak, R Barriales-Villa, TP Abraham… - The Lancet, 2020 - thelancet.com
Background Cardiac muscle hypercontractility is a key pathophysiological abnormality in
hypertrophic cardiomyopathy, and a major determinant of dynamic left ventricular outflow …

Myosin inhibition in patients with obstructive hypertrophic cardiomyopathy referred for septal reduction therapy

MY Desai, A Owens, JB Geske, K Wolski… - Journal of the American …, 2022 - jacc.org
Background Septal reduction therapy (SRT), surgical myectomy or alcohol ablation, is
recommended for obstructive hypertrophic cardiomyopathy (oHCM) patients with intractable …

JCS/JHRS 2019 guideline on non-pharmacotherapy of cardiac arrhythmias

A Nogami, T Kurita, H Abe, K Ando, T Ishikawa… - Circulation …, 2021 - jstage.jst.go.jp
Pacemaker treatment for bradyarrhythmia was first approved for national health insurance
coverage in Japan in 1974, and its use rapidly became widespread thereafter …

Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity

AR Harper, A Goel, C Grace, KL Thomson… - Nature …, 2021 - nature.com
Hypertrophic cardiomyopathy (HCM) is a common, serious, genetic heart disorder. Rare
pathogenic variants in sarcomere genes cause HCM, but with unexplained phenotypic …

2018 ACC/AHA/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay: a report of the American College of …

FM Kusumoto, MH Schoenfeld, C Barrett… - Journal of the American …, 2019 - jacc.org
The recommendations listed in this guideline are, whenever possible, evidence based. An
initial extensive evidence review, which included literature derived from research involving …

[HTML][HTML] 2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest …

MK Stiles, AAM Wilde, DJ Abrams, MJ Ackerman… - Heart Rhythm, 2021 - Elsevier
This international multidisciplinary document intends to provide clinicians with evidence-
based practical patient-centered recommendations for evaluating patients and decedents …