Heme oxygenase-1 (HO-1) is an inducible intracellular enzyme that is expressed in
response to a variety of stimuli to degrade heme, which generates the biologically active …

Abstract Heme oxygenase-1 (HO-1) is considered to be the main protein in diseases arising
as a result of oxidative and inflammatory insults. Tremendous research has been carried out …

Redox signaling regulates physiological self-renewal, proliferation, migration and
differentiation in gastrointestinal epithelium by modulating Wnt/β-catenin and Notch …

Heme oxygenases are composed of two isozymes, Hmox1 and Hmox2, that catalyze the
degradation of heme to carbon monoxide (CO), ferrous iron, and biliverdin, the latter of …

Abstract Heme oxygenase-1 (HO-1) is a rate-limiting enzyme catalyzing oxidative
degradation of cellular heme to liberate free iron, carbon monoxide (CO) and biliverdin in …

Heat stress negatively affects reproduction in cattle by disrupting the normal function of
ovarian granulosa cells (GCs), ultimately leading to oxidative damage and cell death via …

This article reviews the pathogenic mechanism of non-steroidal anti-inflammatory drug
(NSAID)-induced gastric damage, focusing on the relation between cyclooxygenase (COX) …

Reactive oxygen species (ROS) can be both beneficial and deleterious. Under normal
physiological conditions, ROS production is tightly regulated, and ROS participate in both …

Nature is full of examples of symbiotic relationships. The critical symbiotic relation between
host and mutualistic bacteria is attracting increasing attention to the degree that the gut …

Abstract Significance: Heme oxygenase-1 (HMOX1) plays a critical role in the protection of
cells, and the inducible enzyme is implicated in a spectrum of human diseases. The …