The upsurge in the need of targeted controlled drug delivery (TCDD) has led to the invention
of remarkable biomaterials with improved biocompatibility and biodegradability. In recent …

Photoacoustic tomography (PAT) can offer structural, functional and molecular contrasts at
scalable observation level. By ultrasonically overcoming the strong optical scattering, this …

One major challenge in nanomedicine is the selective delivery of nanoparticles to diseased
tissues. Nanoparticle delivery systems require targeting for specific delivery to pathogenic …

Brain tumors are a diverse group of neoplasms that often carry a poor prognosis for patients.
Despite tremendous efforts to develop diagnostic tools and therapeutic avenues, the …

The blood–brain barrier (BBB) has a significant contribution to homeostasis and protection
of the CNS. However, it also limits the crossing of therapeutics and thereby complicates the …

Chemotherapy is commonly associated with limited effectiveness and unwanted side effects
in normal cells and tissues, due to the lack of specificity of therapeutic agents to cancer cells …

Nanogels (or nanohydrogels) have been extensively investigated as one of the most
promising nanoparticulate biomedical platforms owing to their advantageous properties that …

Abstract Changes of physiological pH are correlated with several pathologies, therefore the
development of more effective medical pH imaging methods is of paramount importance …

Multi-Spectral Optoacoustic Tomography (MSOT) merges the power of high-resolution
imaging at tissue depths of several millimeters to centimeters with the advantages of optical …

Current neuroimaging provides detailed anatomic and functional evaluation of brain tumors,
allowing for improved diagnostic and prognostic capabilities. Some challenges persist even …