Regulated cell death (RCD) is a critical and active process that is controlled by specific
signal transduction pathways and can be regulated by genetic signals or drug interventions …

Although chromosome mis-segregation is a hallmark of cancer cells, its genetic basis and
role in malignant transformation remain poorly understood. In recent years, several mouse …

The spindle assembly checkpoint (SAC) is essential for proper sister chromatid segregation.
Defects in this checkpoint can lead to chromosome missegregation and aneuploidy. An …

Cantharidin is an active constituent of mylabris, a traditional Chinese medicine. It is a potent
and selective inhibitor of protein phosphatase 2A (PP2A) that plays an important role in …

Nitrogen (N) deficiency causes early leaf senescence, resulting in accelerated whole-plant
maturation and severely reduced crop yield. However, the molecular mechanisms …

Most human tumors have abnormal numbers of chromosomes, a condition known as
aneuploidy. The mitotic checkpoint is an important mechanism that prevents aneuploidy by …

Cantharidin (CTD) is a traditional Chinese medicine and an effective component isolated
from blister beetle, and it has been demonstrated to have anticancer, antibiotic, antivirus …

Mitotic catastrophe is a mechanism of cell death characterized by the occurrence of aberrant
mitosis with the formation of large cells that contain multiple nuclei, which are …

Abstract Background and Aim: Several recent studies have reported that liver cirrhosis (LC)
can be ameliorated, but few adequate strategies are available against liver fibrosis …

Anni 2.0 is an online tool (http://biosemantics. org/anni/) to aid the biomedical researcher
with a broad range of information needs. Anni provides an ontology-based interface to …