Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via
a balance between bone formation by osteoblasts and resorption by osteoclasts. These …

Research on astronaut health and model organisms have revealed six features of
spaceflight biology that guide our current understanding of fundamental molecular changes …

Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses
myriad biomedical challenges to the human body, which are becoming increasingly relevant …

Telomeres are specialized nucleoprotein structures at the ends of linear chromosomes. The
progressive shortening of steady-state telomere length in normal human somatic cells is a …

The recent acceleration of commercial, private and multi-national spaceflight has created an
unprecedented level of activity in low Earth orbit, concomitant with the largest-ever number …

Abstract The SpaceX Inspiration4 mission provided a unique opportunity to study the impact
of spaceflight on the human body. Biospecimen samples were collected from four crew …

While the benefits of physical exercise for a healthy aging are well-recognized, a growing
body of evidence shows that sedentary behavior has deleterious health effects …

Spaceflight-induced changes in astronaut telomeres have garnered significant attention in
recent years. While plants represent an essential component of future long-duration space …

Alterations in the circadian system are characteristic of aging on Earth. With the decline in
physiological processes due to aging, several health concerns including vision loss …

The carcinogenic risk from space radiation has always been a health risk issue of great
concern during space exploration. In recent years, a large number of cellular and animal …