Cleavable linkers in chemical biology
G Leriche, L Chisholm, A Wagner - Bioorganic & medicinal chemistry, 2012 - Elsevier
Interest in cleavable linkers is growing due to the rapid development and expansion of
chemical biology. The chemical constrains imposed by the biological conditions cause …
chemical biology. The chemical constrains imposed by the biological conditions cause …
Detecting RNA and DNA with templated chemical reactions
AP Silverman, ET Kool - Chemical reviews, 2006 - ACS Publications
Sensing nucleic acid sequences is critical in modern-day biology and medicine, and is likely
to continue to increase in importance over the next 10r20 years. The current uses for …
to continue to increase in importance over the next 10r20 years. The current uses for …
Reactions templated by nucleic acids: more ways to translate oligonucleotide‐based instructions into emerging function
K Gorska, N Winssinger - Angewandte Chemie International …, 2013 - Wiley Online Library
The programmability of oligonucleotide recognition offers an attractive platform to direct the
assembly of reactive partners that can engage in chemical reactions. Recently, significant …
assembly of reactive partners that can engage in chemical reactions. Recently, significant …
Signal amplification by allosteric catalysis
In this article we unify a series of recent studies on bio‐and chemosensors under a single
signaling strategy: signal amplification by allosteric catalysis (SAAC). The SAAC strategy …
signaling strategy: signal amplification by allosteric catalysis (SAAC). The SAAC strategy …
DNA-catalyzed transfer of a reporter group
TN Grossmann, O Seitz - Journal of the American Chemical …, 2006 - ACS Publications
Herein we describe a novel DNA-catalyzed transfer of a reporter group from a donating to an
accepting oligo-peptide nucleic acid (PNA), generating high catalytic turnover numbers in a …
accepting oligo-peptide nucleic acid (PNA), generating high catalytic turnover numbers in a …
[PDF][PDF] Achieving turnover in DNA‐templated reactions
TN Grossmann, A Strohbach, O Seitz - ChemBioChem, 2008 - academia.edu
Templated reactions have frequently been applied in nucleic acid chemistry as well as in
synthetic chemistry to facilitate conversions that proceed less efficiently when performed in …
synthetic chemistry to facilitate conversions that proceed less efficiently when performed in …
Supramolecular Bidentate Ligands by Metal‐Directed in situ Formation of Antiparallel β‐Sheet Structures and Application in Asymmetric Catalysis
AC Laungani, JM Slattery, I Krossing… - Chemistry–A European …, 2008 - Wiley Online Library
The principles of protein structure design, molecular recognition, and supramolecular and
combinatorial chemistry have been applied to develop a convergent metal‐ion‐assisted self …
combinatorial chemistry have been applied to develop a convergent metal‐ion‐assisted self …
As fast and selective as enzymatic ligations: unpaired nucleobases increase the selectivity of DNA‐controlled native chemical PNA ligation
S Ficht, C Dose, O Seitz - ChemBioChem, 2005 - Wiley Online Library
DNA‐controlled reactions offer interesting opportunities in biological, chemical, and
nanosciences. In practical applications, such as in DNA sequence analysis, the sequence …
nanosciences. In practical applications, such as in DNA sequence analysis, the sequence …