Comparative and evolutionary physiology of vasopressin/oxytocin-type neuropeptide signaling in invertebrates

EA Odekunle, MR Elphick - Frontiers in Endocrinology, 2020 - frontiersin.org
The identification of structurally related hypothalamic hormones that regulate blood pressure
and diuresis (vasopressin, VP; CYFQNCPRG-NH2) or lactation and uterine contraction …

Neuropeptide signalling systems–an underexplored target for venom drug discovery

HC Mendel, Q Kaas, M Muttenthaler - Biochemical pharmacology, 2020 - Elsevier
Neuropeptides are signalling molecules mainly secreted from neurons that act as
neurotransmitters or peptide hormones to affect physiological processes and modulate …

Ancient role of sulfakinin/cholecystokinin-type signalling in inhibitory regulation of feeding processes revealed in an echinoderm

AB Tinoco, A Barreiro-Iglesias, LAY Guerra, J Delroisse… - Elife, 2021 - elifesciences.org
Abstract Sulfakinin (SK)/cholecystokinin (CCK)-type neuropeptides regulate feeding and
digestion in protostomes (eg insects) and chordates. Here, we characterised SK/CCK-type …

Molecular and functional characterization of somatostatin-type signalling in a deuterostome invertebrate

Y Zhang, LA Yañez Guerra, M Egertová… - Open …, 2020 - royalsocietypublishing.org
Somatostatin (SS) and allatostatin-C (ASTC) are structurally and evolutionarily related
neuropeptides that act as inhibitory regulators of physiological processes in mammals and …

A Putative Role of Vasopressin/Oxytocin-Type Neuropeptide in Osmoregulation and Feeding Inhibition of Apostichopus japonicus

X Cong, H Liu, Y Zheng, M Chen - International Journal of Molecular …, 2023 - mdpi.com
Vasopressin/oxytocin (VP/OT)-type neuropeptide is an ancient neurophysin-associated
neuropeptide and has been intensively studied to be involved in multiple physiological …

Discovery and functional characterization of neuropeptides in crinoid echinoderms

A Aleotti, IC Wilkie, LA Yañez-Guerra… - Frontiers in …, 2022 - frontiersin.org
Neuropeptides are one of the largest and most diverse families of signaling molecules in
animals and, accordingly, they regulate many physiological processes and behaviors …

Nervous system development and neuropeptides characterization in embryo and larva: insights from a non-chordate deuterostome, the sea cucumber Apostichopus …

Y Zheng, X Cong, H Liu, Y Wang, KB Storey, M Chen - Biology, 2022 - mdpi.com
Simple Summary Pentamerous radial symmetrical echinoderm adults develop from
bilaterally symmetrical larvae and are a great model for understanding the origin and …

Somatostatin-type and allatostatin-C–type neuropeptides are paralogous and have opposing myoregulatory roles in an echinoderm

Y Zhang, LA Yañez-Guerra… - Proceedings of the …, 2022 - National Acad Sciences
Somatostatin (SS) and allatostatin-C (ASTC) are inhibitory neuropeptides in chordates and
protostomes, respectively, which hitherto were identified as orthologs. However …

Receptor deorphanization in an echinoderm reveals kisspeptin evolution and relationship with SALMFamide neuropeptides

N Escudero Castelán, DC Semmens, LAY Guerra… - BMC biology, 2022 - Springer
Background Kisspeptins are neuropeptides that regulate reproductive maturation in
mammals via G-protein-coupled receptor-mediated stimulation of gonadotropin-releasing …

Uncovering the seasonal brain: liquid chromatography-tandem mass spectrometry (LC-MS/MS) as a biochemical approach for studying seasonal social behaviors

KM Munley, KL Wade, DS Pradhan - Hormones and Behavior, 2022 - Elsevier
Many animals show pronounced changes in physiology and behavior across the annual
cycle, and these adaptations enable individuals to prioritize investing in the neuroendocrine …