Older adult participation in cancer clinical trials: a systematic review of barriers and interventions

MS Sedrak, RA Freedman, HJ Cohen… - CA: a cancer journal …, 2021 - Wiley Online Library
Cancer is a disease of aging and, as the world's population ages, the number of older
persons with cancer is increasing and will make up a growing share of the oncology …

Functional versus chronological age: geriatric assessments to guide decision making in older patients with cancer

E Soto-Perez-de-Celis, D Li, Y Yuan, YM Lau… - The Lancet …, 2018 - thelancet.com
As the worldwide population ages, oncologists are often required to make difficult and
complex decisions regarding the treatment of older people (aged 65 years and older) with …

[HTML][HTML] Integrated Geriatric Assessment and Treatment Effectiveness (INTEGERATE) in older people with cancer starting systemic anticancer treatment in Australia: a …

WK Soo, MT King, A Pope, P Parente… - The Lancet Healthy …, 2022 - thelancet.com
Background The effectiveness of comprehensive geriatric assessment (CGA) in improving
health outcomes in cancer settings is unclear. We evaluated whether CGA can improve …

Efficacy of reduced-intensity chemotherapy with oxaliplatin and capecitabine on quality of life and cancer control among older and frail patients with advanced …

PS Hall, D Swinson, DA Cairns, JS Waters… - JAMA …, 2021 - jamanetwork.com
Importance Older and/or frail patients are underrepresented in landmark cancer trials.
Tailored research is needed to address this evidence gap. Objective The GO2 randomized …

Early relapse of follicular lymphoma after rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone defines patients at high risk for death: an analysis …

C Casulo, M Byrtek, KL Dawson, X Zhou… - Journal of Clinical …, 2015 - ascopubs.org
Purpose Twenty percent of patients with follicular lymphoma (FL) experience progression of
disease (POD) within 2 years of initial chemoimmunotherapy. We analyzed data from the …

International Society of Geriatric Oncology consensus on geriatric assessment in older patients with cancer

H Wildiers, P Heeren, M Puts, E Topinkova… - Journal of clinical …, 2014 - ascopubs.org
Purpose To update the International Society of Geriatric Oncology (SIOG) 2005
recommendations on geriatric assessment (GA) in older patients with cancer. Methods SIOG …

Use of a comprehensive geriatric assessment for the management of elderly patients with advanced non–small-cell lung cancer: the phase III randomized ESOGIA …

R Corre, L Greillier, H Le Caër… - Journal of Clinical …, 2016 - ascopubs.org
Purpose Comprehensive geriatric assessment (CGA) is recommended to assess the
vulnerability of elderly patients, but its integration in cancer treatment decision making has …

Communication with older patients with cancer using geriatric assessment: a cluster-randomized clinical trial from the National Cancer Institute Community Oncology …

SG Mohile, RM Epstein, A Hurria, CE Heckler… - JAMA …, 2020 - jamanetwork.com
Importance Older patients with cancer and their caregivers worry about the effects of cancer
treatment on aging-related domains (eg, function and cognition). Quality conversations with …

Chemotherapy for advanced gastric cancer

AD Wagner, NLX Syn, M Moehler… - Cochrane database …, 2017 - cochranelibrary.com
Background Gastric cancer is the fifth most common cancer worldwide. In" Western"
countries, most people are either diagnosed at an advanced stage, or develop a relapse …

[HTML][HTML] Patient preferences for treatment outcomes in oncology with a focus on the older patient—a systematic review

PAL Seghers, A Wiersma, S Festen, ME Stegmann… - Cancers, 2022 - mdpi.com
Simple Summary In oncology, treatment outcomes can be competing, which means that one
treatment could benefit one outcome, like survival, and negatively influence another, like …