Ga‐catalyzed temperature‐dependent oxazolidinone/piperazine synthesis from phenyl aziridines involving a divergent ligand‐assisted mechanism

MDG Billacura, RD Lewis, N Bricklebank… - Advanced Synthesis …, 2023 - Wiley Online Library
Application of a binary Ga‐based catalyst system for the coupling of CO2 and aziridines to
form oxazolidinones is presented. It has been possible to optimize the catalyst system for the …

C1 functionalization of imidazo heterocycles via carbon dioxide fixation

M Fragkiadakis, PK Anastasiou, I Volyrakis… - Chemical …, 2023 - pubs.rsc.org
Utilizing CO2 as a one-carbon building block in the preparation of high-value chemical
entities is a cornerstone of modern organic synthesis. Herein, we exemplify this strategy …

Biocatalytic Construction of Spiro-Oxazolidinones via Halohydrin Dehalogenase-Catalyzed Ring Expansion of Spiro-Epoxides

JM Ma, YF Wang, RP Miao, X Jin, HH Wang… - ACS …, 2024 - ACS Publications
Spiro-oxazolidinones are highly valuable compounds in the fields of medicinal and organic
chemistry; however, the methods for synthesizing these compounds have not been well …

Antibacterial Properties and Computational Insights of Potent Novel Linezolid-Based Oxazolidinones

MS Malik, S Faazil, MA Alsharif, QM Sajid Jamal… - Pharmaceuticals, 2023 - mdpi.com
The mounting evidence of bacterial resistance against commonly prescribed antibiotics
warrants the development of new antibacterial drugs on an urgent basis. Linezolid, an …

Sequential Glaser reaction–diastereoselective cyclocarboxylation of propargylamines with CO 2: a green catalytic access to bis-oxazolidinonedienes and their …

F Mele, AM Constantin, F Sacchelli, D Schiroli… - Green …, 2024 - pubs.rsc.org
A novel catalytic route for the direct synthesis of bis-oxazolidinonedienes from CO2 and
propargylic amines is presented. An inexpensive copper catalyst promotes the Glaser …

Organocatalytic Enantioselective Chloroiminocyclization for the Synthesis of Imidazoline

Q Guo, Z Lai, Z Tian, R Tang, T Ding, X Jiang - Organic Letters, 2024 - ACS Publications
Imidazoline is an important scaffold in organic synthesis and a pharmacophore in medicinal
chemistry. We apply basic imines as nucleophiles for the catalytic asymmetric …

A Mechanistic Insight on CuI‐Catalyzed Synthesis of Oxazolidinones through a Four‐Component Reaction

R Pich, S Mallet‐Ladeira, P Lavedan… - Advanced Synthesis …, 2024 - Wiley Online Library
In this contribution, we describe a straightforward and efficient synthesis of oxazolidin‐2‐
ones through a Cu (I)‐catalyzed four‐component coupling of amines, aldehydes, terminal …

Quantitative evaluation of H-donating abilities of C (sp 3)–H bonds of nitrogen-containing heterocycles in hydrogen atom transfer reaction

YH Fu, T Jia, GB Shen, XQ Zhu - RSC advances, 2023 - pubs.rsc.org
Nitrogen-containing heterocycles are an important class of antioxidants, and their reactivity
and selectivity in hydrogen atom reactions have attracted significant interest from chemists …

Biocatalytic Regio‐and Enantiocomplementary Synthesis of Chiral Aryloxazolidinones

XY Zhou, YF Wang, HK Fu, HH Wang… - Advanced Synthesis …, 2024 - Wiley Online Library
We described the protein engineering of the halohydrin dehalogenase HheG to enhance its
R enantioselectivity for the synthesis of chiral 4‐aryloxazolidinones via α‐regioselective ring …

[HTML][HTML] Synthesis and density functional theory study of functionalized Oxazolidine-2-ones using a novel MnFe2O4@ SiO2-SiO3H magnetic nanocatalyst

S Nikmanesh, F Heidarizadeh, Z Mahdavifar - Journal of Saudi Chemical …, 2024 - Elsevier
This study introduces MnFe 2 O 4@ SiO 2-SiO 3 H as a novel magnetic catalyst and
thoroughly investigates its structure, catalytic activity, and reusability. The synthesis of the …