[HTML][HTML] 30 years of microfluidics

N Convery, N Gadegaard - Micro and Nano Engineering, 2019 - Elsevier
Microfluidics provides a great opportunity to create devices capable of outperforming
classical techniques in biomedical and chemical research. In this review, the origins of this …

Point of care diagnostics: status and future

V Gubala, LF Harris, AJ Ricco, MX Tan… - Analytical …, 2012 - ACS Publications
We review point-of-care (POC) diagnostics, in vitro diagnostic (IVD) tests that do not involve
the use of laboratory staff and facilities to provide the result. The analytical “targets” include …

Immobilization of antibodies and enzymes on 3-aminopropyltriethoxysilane-functionalized bioanalytical platforms for biosensors and diagnostics

SK Vashist, E Lam, S Hrapovic, KB Male… - Chemical …, 2014 - ACS Publications
Biosensing and diagnostic platforms with high sensitivity, specificity, and fast response time
are based on immobilized biomolecules such as antibodies (Abs), aptamers, enzymes …

Microfluidics: recent advances toward lab‐on‐chip applications in bioanalysis

B Sharma, A Sharma - Advanced engineering materials, 2022 - Wiley Online Library
Microfluidics is an emerging technology of flow and control of fluids in microscale volume
that offers highly specialized solutions to rapid, sensitive, noninvasive analysis and …

Engineered nanomaterials and human health: Part 1. Preparation, functionalization and characterization (IUPAC Technical Report)

V Gubala, LJ Johnston, Z Liu, H Krug… - Pure and Applied …, 2018 - degruyter.com
Nanotechnology is a rapidly evolving field, as evidenced by the large number of publications
on the synthesis, characterization, and biological/environmental effects of new nano-sized …

Developing porous microneedles patch for the detection of wound infections

W Xue, J Na, L Zhang, Y Zu, F Lin - Advanced Materials …, 2024 - Wiley Online Library
Wound infections caused by invasive pathogens become an increasing global challenge
health. Porous microneedles (MNs) present distinctive advantages for non‐invasive and in …

Integration of functional materials and surface modification for polymeric microfluidic systems

M Kitsara, J Ducrée - Journal of Micromechanics and …, 2013 - iopscience.iop.org
The opportunity for the commercialization of microfluidic systems has surged over the recent
decade, primarily for medical and the life science applications. This positive development …

Antibody immobilization and surface functionalization chemistries for immunodiagnostics

SK Vashist, JHT Luong - Handbook of Immunoassay Technologies, 2018 - Elsevier
The immobilization of antibodies on sensing platforms is the first critical step in the
development of immunoassays with excellent bioanalytical performance. The ideal …

At-line bioprocess monitoring by immunoassay with rotationally controlled serial siphoning and integrated supercritical angle fluorescence optics

CE Nwankire, GG Donohoe, X Zhang, J Siegrist… - Analytica chimica …, 2013 - Elsevier
In this paper we report a centrifugal microfluidic “lab-on-a-disc” system for at-line monitoring
of human immunoglobulin G (hIgG) in a typical bioprocess environment. The novelty of this …

A 1024-sample serum analyzer chip for cancer diagnostics

JL Garcia-Cordero, SJ Maerkl - Lab on a Chip, 2014 - pubs.rsc.org
We present a platform that combines microarrays and microfluidic techniques to measure
four protein biomarkers in 1024 serum samples for a total of 4096 assays per device …