MicroRNAs are post-transcriptional regulators of gene expression, crucial for neuronal
differentiation, survival, and activity. Age-related dysregulation of microRNA biogenesis …

Cell division and organismal development are exquisitely orchestrated and regulated
processes. The dysregulation of the molecular mechanisms underlying these processes …

R-loops, which consist of a DNA-RNA hybrid and a displaced DNA strand, are known to
threaten genome integrity. To counteract this, different mechanisms suppress R-loop …

RNA-sequencing has led to a spectacular increase in the repertoire of bacterial sRNAs and
improved our understanding of their biological functions. Bacterial sRNAs have also been …

Genome editing tools have the potential to change the genomic architecture of a genome at
precise locations, with desired accuracy. These tools have been efficiently used for trait …

The human genome is 'pervasively transcribed'leading to a complex array of non-coding
RNAs (ncRNAs) that far outnumber coding mRNAs. ncRNAs have regulatory roles in …

Ovarian cancer (OC) is one of the leading causes of cancer-related deaths in women. Most
patients are diagnosed with advanced epithelial OC in their late 60s, and early-onset adult …

Regulation of gene expression by small non-coding RNAs, such as miRNAs and siRNAs, is
an inherent part of complex biological processes that allow function and survival of …

The RNA interference pathway (RNAi) is executed by two core enzymes, Dicer and
Argonaute, for accomplishing a tailored transcriptional and post-transcriptional gene …

The assortment of cellular microRNAs (“microRNAome”) is a vital readout of cellular
homeostasis, but the mechanisms that regulate the microRNAome are poorly understood …