Brainstem modulation of large-scale intrinsic cortical activity correlations

RL van den Brink, T Pfeffer, TH Donner - Frontiers in human …, 2019 - frontiersin.org
Brain activity fluctuates continuously, even in the absence of changes in sensory input or
motor output. These intrinsic activity fluctuations are correlated across brain regions and are …

Network structure of the mouse brain connectome with voxel resolution

L Coletta, M Pagani, JD Whitesell, JA Harris… - Science …, 2020 - science.org
Fine-grained descriptions of brain connectivity are required to understand how neural
information is processed and relayed across spatial scales. Previous investigations of the …

Coupling of pupil-and neuronal population dynamics reveals diverse influences of arousal on cortical processing

T Pfeffer, C Keitel, DS Kluger, A Keitel, A Russmann… - elife, 2022 - elifesciences.org
Fluctuations in arousal, controlled by subcortical neuromodulatory systems, continuously
shape cortical state, with profound consequences for information processing. Yet, how …

Circuit mechanisms for the chemical modulation of cortex-wide network interactions and behavioral variability

T Pfeffer, A Ponce-Alvarez, K Tsetsos… - Science …, 2021 - science.org
Influential theories postulate distinct roles of catecholamines and acetylcholine in cognition
and behavior. However, previous physiological work reported similar effects of these …

[HTML][HTML] The effects of propofol anaesthesia on molecular-enriched networks during resting-state and naturalistic listening

T Lawn, D Martins, O O'Daly, S Williams, M Howard… - NeuroImage, 2023 - Elsevier
Placing a patient in a state of anaesthesia is crucial for modern surgical practice. However,
the mechanisms by which anaesthetic drugs, such as propofol, impart their effects on …

Rhythmicity of neuronal oscillations delineates their cortical and spectral architecture

V Myrov, F Siebenhühner, JJ Juvonen… - Communications …, 2024 - nature.com
Neuronal oscillations are commonly analyzed with power spectral methods that quantify
signal amplitude, but not rhythmicity or 'oscillatoriness' per se. Here we introduce a new …

Dopamine D2/3 binding potential modulates neural signatures of working memory in a load-dependent fashion

A Salami, DD Garrett, A Wåhlin… - Journal of …, 2019 - Soc Neuroscience
Dopamine (DA) modulates corticostriatal connections. Studies in which imaging of the DA
system is integrated with functional imaging during cognitive performance have yielded …

The modulation of brain network integration and arousal during exploration

N Tardiff, JD Medaglia, DS Bassett… - NeuroImage, 2021 - Elsevier
There is growing interest in how neuromodulators shape brain networks. Recent
neuroimaging studies provide evidence that brainstem arousal systems, such as the locus …

Target detection increases pupil diameter and enhances memory for background scenes during multi-tasking

KM Swallow, YV Jiang, EB Riley - Scientific reports, 2019 - nature.com
Attending to targets in a detection task can facilitate memory for concurrently presented
information, a phenomenon known as the attentional boost effect. One account of the …

[HTML][HTML] Pupil-based states of brain integration across cognitive states

V Mäki-Marttunen - Neuroscience, 2021 - Elsevier
Arousal is a potent mechanism that provides the brain with functional flexibility and
adaptability to external conditions. Within the wake state, arousal levels driven by activity in …