BACKGROUND Two developments in distinct fields are converging to create interest in
discovering small molecules from the human microbiome. First, the use of genomics to guide …

Covering: up to 2017. Natural products are important secondary metabolites produced by
bacterial and fungal species that play important roles in cellular growth and signaling …

The strong restriction barrier present in Staphylococcus aureus and Staphylococcus
epidermidis has limited functional genomic analysis to a small subset of strains that are …

Staphylococcus aureus, a major human pathogen, has been the cause of serious infectious
diseases with a high mortality rate. Although genetics is a key means to study S. aureus …

Staphylococcus aureus is a facultative anaerobic Gram‐positive coccus and a member of
the normal skin flora as well as the nasal passages of humans. S. aureus is also the …

Staphylococcus aureus is a significant cause of human infection. Here, we demonstrate that
mutations in the transcriptional repressor of purine biosynthesis, purR, enhance the …

Most strains of Staphylococcus aureus and Staphylococcus epidermidis possess a strong
restriction barrier that hinders exchange of DNA. Recently, major advances have been made …

In bacterial two‐component regulatory systems (TCSs), dephosphorylation of
phosphorylated response regulators is essential for resetting the activated systems to the …

Retraction of flawed articles is an important mechanism for correction of the scientific
literature. We recently reported that the majority of retractions are associated with scientific …

In the last 10 years, the barriers preventing the uptake of foreign DNA by clinical
Staphylococcus aureus isolates have been identified and powerful mutagenesis techniques …