Sleep disturbances as the hallmark of PTSD: where are we now?

A Germain - American Journal of Psychiatry, 2013 - Am Psychiatric Assoc
The hypothesis that rapid eye movement (REM) sleep disturbances are the hallmark of
posttraumatic stress disorder (PTSD), proposed by Ross and colleagues in 1989, has …

Consequences of sleep deprivation.

J Orzeł-Gryglewska - International Journal of Occupational …, 2010 - search.ebscohost.com
This paper presents the history of research and the results of recent studies on the effects of
sleep deprivation in animals and humans. Humans can bear several days of continuous …

Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application

MJ Millan - Pharmacology & therapeutics, 2006 - Elsevier
Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

The role of rapid eye movement sleep for amygdala-related memory processing

L Genzel, VI Spoormaker, BN Konrad… - Neurobiology of learning …, 2015 - Elsevier
Over the years, rapid eye movement (REM) sleep has been associated with general memory
consolidation, specific consolidation of perceptual, procedural, emotional and fear …

Astrocyte-derived adenosine and A1 receptor activity contribute to sleep loss-induced deficits in hippocampal synaptic plasticity and memory in mice

C Florian, CG Vecsey, MM Halassa… - Journal of …, 2011 - Soc Neuroscience
Sleep deprivation (SD) can have a negative impact on cognitive function, but the mechanism
(s) by which SD modulates memory remains unclear. We have previously shown that …

[HTML][HTML] Paradoxical sleep deprivation: neurochemical, hormonal and behavioral alterations. Evidence from 30 years of research

S Tufik, ML Andersen, LRA Bittencourt… - Anais da Academia …, 2009 - SciELO Brasil
Sleep comprises approximately one-third of a person's lifetime, but its impact on health and
medical conditions remains partially unrecognized. The prevalence of sleep disorders is …

Sleep deprivation impairs spatial working memory and reduces hippocampal AMPA receptor phosphorylation

R Hagewoud, R Havekes, A Novati… - Journal of sleep …, 2010 - Wiley Online Library
Sleep is important for brain function and cognitive performance. Sleep deprivation (SD) may
affect subsequent learning capacity and ability to form new memories, particularly in the …

Experimental sleep deprivation as a tool to test memory deficits in rodents

V Colavito, PF Fabene, G Grassi-Zucconi… - Frontiers in systems …, 2013 - frontiersin.org
Paradigms of sleep deprivation (SD) and memory testing in rodents (laboratory rats and
mice) are here reviewed. The vast majority of these studies have been aimed at …

Consolidative mechanisms of emotional processing in REM sleep and PTSD

ALA Murkar, J De Koninck - Sleep medicine reviews, 2018 - Elsevier
Research suggests sleep plays a role in the consolidation of recently acquired memories for
long-term storage. rapid eye movement (REM) sleep has been shown to play a complex role …

Rapid eye movement sleep deprivation selectively impairs recall of fear extinction in hippocampus-independent tasks in rats

J Fu, P Li, X Ouyang, C Gu, Z Song, J Gao, L Han… - Neuroscience, 2007 - Elsevier
Previous studies have shown that rapid eye movement (REM) sleep deprivation (RSD)
exerts a detrimental effect on some memory tasks. However, whether post-learning RSD …