Bio-markers, such as ions, small molecules, nucleic acids, peptides, proteins and cells,
participate in the construction of living organisms and play important roles in biological …

Biomimetic solid-state nanochannels enable new modalities for biosensing. In the last
decade, these nanofluidic architectures have been widely studied due to their rapid and …

Nanochannel technology has emerged as a powerful tool for label‐free and highly sensitive
detection of protein folding/unfolding status. However, utilizing the inner walls of a …

Compared with free miRNAs in blood, miRNAs in exosomes have higher abundance and
stability. Therefore, miRNAs in exosomes can be regarded as an ideal tumor marker for …

As one of the significant intracellular signaling molecules, hydrogen peroxide (H2O2)
regulates some vital biological processes. However, it remains a challenge to develop …

Owing to the urgent need for electrochemical analysis and sensing of trace target molecules
in various fields such as medical diagnosis, agriculture and food safety, and environmental …

Bioinspired nanochannels have emerged as a powerful tool for bioengineering and
biomedical research due to their robust mechanical and controllable chemical properties …

Single-cell interrogation with the solid-state nanoprobes enables understanding of the
linkage between cellular behavior and heterogeneity. Herein, inspired by the charge …

In recent years, the intensive studies have been devoted to nanopores due to their unique
charge transport properties including ion permselectivity, ion concentration polarization, and …

Solid-state nanopores/nanochannels, with their high stability, tunable geometry, and
controllable surface chemistry, have recently become an important tool for constructing …