Nanopore-based technologies beyond DNA sequencing
Inspired by the biological processes of molecular recognition and transportation across
membranes, nanopore techniques have evolved in recent decades as ultrasensitive …
membranes, nanopore techniques have evolved in recent decades as ultrasensitive …
Emerging approaches to DNA data storage: challenges and prospects
With the total amount of worldwide data skyrocketing, the global data storage demand is
predicted to grow to 1.75× 1014 GB by 2025. Traditional storage methods have difficulties …
predicted to grow to 1.75× 1014 GB by 2025. Traditional storage methods have difficulties …
Engineering biological nanopore approaches toward protein sequencing
Biotechnological innovations have vastly improved the capacity to perform large-scale
protein studies, while the methods we have for identifying and quantifying individual proteins …
protein studies, while the methods we have for identifying and quantifying individual proteins …
Engineering precise sequence-defined polymers for advanced functions
Unlike natural macromolecules (eg, nucleic acids and proteins) possessing precisely
defined molar mass, chain sequence, chirality, and topology, synthetic polymers are typically …
defined molar mass, chain sequence, chirality, and topology, synthetic polymers are typically …
Sequence-and stereo-defined macromolecules: properties and emerging functionalities
R Szweda - Progress in Polymer Science, 2023 - Elsevier
Natural macromolecules, such as proteins and nucleic acids, display various complex
functionalities in biological systems. These functionalities depend on the macromolecular …
functionalities in biological systems. These functionalities depend on the macromolecular …
Sculpting conducting nanopore size and shape through de novo protein design
Transmembrane β-barrels have considerable potential for a broad range of sensing
applications. Current engineering approaches for nanopore sensors are limited to naturally …
applications. Current engineering approaches for nanopore sensors are limited to naturally …
Abiotic peptides as carriers of information for the encoding of small-molecule library synthesis
Encoding small-molecule information in DNA has been leveraged to accelerate the
discovery of ligands for therapeutic targets such as proteins. However, oligonucleotide …
discovery of ligands for therapeutic targets such as proteins. However, oligonucleotide …
Nanopore analysis of salvianolic acids in herbal medicines
P Fan, S Zhang, Y Wang, T Li, H Zhang… - Nature …, 2024 - nature.com
Natural herbs, which contain pharmacologically active compounds, have been used
historically as medicines. Conventionally, the analysis of chemical components in herbal …
historically as medicines. Conventionally, the analysis of chemical components in herbal …
Super‐Resolution Detection of DNA Nanostructures Using a Nanopore
K Chen, A Choudhary, SE Sandler, C Maffeo… - Advanced …, 2023 - Wiley Online Library
High‐resolution analysis of biomolecules has brought unprecedented insights into
fundamental biological processes and dramatically advanced biosensing. Notwithstanding …
fundamental biological processes and dramatically advanced biosensing. Notwithstanding …
Reading information stored in synthetic macromolecules
The storage of information in synthetic (macro) molecules provides an attractive alternative
for current archival storage media, and the advancements made within this area have …
for current archival storage media, and the advancements made within this area have …