Discovery of 8-hydroxy-2-quinoline carbaldehyde derivatives as inhibitors for M1 aminopeptidase of Leishmania donovani
M1 aminopeptidase is a metallopeptidase that plays a vital role in protein catabolism and
has been identified as a validated drug target in various parasites; however, our …
has been identified as a validated drug target in various parasites; however, our …
Structure of puromycin-sensitive aminopeptidase and polyglutamine binding
S Madabushi, KM Chow, ES Song, A Goswami… - Plos one, 2023 - journals.plos.org
Puromycin-sensitive aminopeptidase (EC 3.4. 11.14, UniProt P55786), a zinc
metallopeptidase belonging to the M1 family, degrades a number of bioactive peptides as …
metallopeptidase belonging to the M1 family, degrades a number of bioactive peptides as …
Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis
Puromycin sensitive aminopeptidase (PSA or NPEPPS) is a M1 class aminopeptidase is
selectively inhibited by the natural product puromycin, an aminonucleoside antibiotic …
selectively inhibited by the natural product puromycin, an aminonucleoside antibiotic …
Advancements in Drug Delivery Systems for Natural Compounds Targeting Metabolic Disorders Associated with Inflammation
R Sam, S Neal - Archives of Gastroenterology Research, 2023 - scientificarchives.com
The global incidence of metabolic disorders is on the rise, posing a significant challenge to
public health. With remarkable advancements in diagnostic tools and clinical procedures …
public health. With remarkable advancements in diagnostic tools and clinical procedures …
[HTML][HTML] Advancements in nanostructure applications for the anticancer delivery of natural compounds
T Rehman, R Tabibur - … of Research in Pharmaceutical Sciences and …, 2024 - rubpub.in
In drug design, compounds and extracts sourced from natural origins continue to play a
crucial role, offering versatile interactions with enzymes, receptors, and metabolic pathways …
crucial role, offering versatile interactions with enzymes, receptors, and metabolic pathways …
[PDF][PDF] Real-World Clinical Data: Shaping Evidence-Based Decision-Making In Diabetes Dosage Forms Powered By Natural Compounds
KJ Rolla - J Med Case Rep Case Series, 2024 - acquaintpublications.com
Real-world studies have emerged as a pivotal source of evidence for evaluating treatment
effectiveness in clinical practice. While randomized clinical trials (RCTs) are the'gold …
effectiveness in clinical practice. While randomized clinical trials (RCTs) are the'gold …
Conformational Changes in Insulin Regulated Aminopeptidase
S Moes - 2021 - diva-portal.org
Around the world the elderly population is growing, and many new challenges are
presenting themselves to the field of pharmacy. Dementia and age-related cognitive decline …
presenting themselves to the field of pharmacy. Dementia and age-related cognitive decline …