Ubiquitination of proteins is a post-translational modification process with many different
cellular functions, including protein stability, immune signaling, antiviral functions and virus …

Type I interferons (IFN‐I) are a group of related proteins that help regulate the activity of the
immune system and play a key role in host defense against viral infections. Upon infection …

Zika and dengue virus nonstructural protein 5 antagonism of STAT2, a critical interferon
signaling transcription factor, to suppress the host interferon response is required for viremia …

African swine fever virus (ASFV) is the causative agent of one of the most lethal diseases
affecting domestic pig and wild boar, which is endangering the swine industry due to its …

Flaviviruses continue to emerge as global health threats. There are currently no Food and
Drug Administration (FDA) approved antiviral treatments for flaviviral infections. Therefore …

African swine fever virus (ASFV) causes a serious disease in domestic pigs and wild boars
and is currently expanding worldwide. No safe and efficacious vaccines against ASFV are …

Zika virus is the latest addition to an ever-growing list of arboviruses that are causing
outbreaks with serious consequences. A few mild cases were recorded between 1960 and …

Yellow fever (YF) is a mosquito-transmitted viral disease that causes tens of thousands of
deaths each year despite the long-standing deployment of an effective vaccine. In its most …

Yellow fever virus (YFV) represents a re-emerging zoonotic pathogen, transmitted by
mosquito vectors to humans from primate reservoirs. Sporadic outbreaks of YFV occur in …

Paramyxoviridae is a viral family within the order of Mononegavirales; they are negative
single-strand RNA viruses that can cause significant diseases in both humans and animals …