Both embryonic and adult stem cells are endowed with a superior capacity to prevent the
accumulation of genetic lesions, repair them, or avoid their propagation to daughter cells …

RNA interference (RNAi), a cellular process through which small RNAs target and regulate
complementary RNA transcripts, has well-characterized roles in post-transcriptional gene …

Micro RNA s (miRNAs) are small regulatory noncoding RNA s that are generated in the
canonical RNA interference (RNA i) pathway. Drosha, DiGeorge syndrome critical region 8 …

Abstract Embryonal tumor with Multilayered Rosettes (ETMR) is a relatively rare but typically
deadly type of brain tumor that occurs mostly in infants. Since the discovery of the …

Regulation of gene expression by small non-coding RNAs, such as miRNAs and siRNAs, is
an inherent part of complex biological processes that allow function and survival of …

microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the
posttranscriptional level, inducing the degradation of the target mRNA or translational …

The endoribonuclease Dicer is a key component of the human RNA interference pathway
and is known for its role in cytoplasmic microRNA production. Recent findings suggest that …

A novel class of small non-coding RNAs called DNA damage response RNAs (DDRNAs)
generated at DNA double-strand breaks (DSBs) in a DROSHA-and DICER-dependent …

Microglia seed the embryonic neuro-epithelium, expand and actively sculpt neuronal circuits
in the developing central nervous system, but eventually adopt relative quiescence and …

The γ phosphorylated form of the histone H2AX (γH2AX) was described more than 40 years
ago and it was demonstrated that phosphorylation of H2AX was one of the first cellular …