Fibrosis is associated with accumulation of excess fibrillar collagen, leading to tissue
dysfunction. Numerous processes, including inflammation, myofibroblast activation, and …

Abstract Background Circular RNAs (circRNAs) are emerging as powerful regulators of
cardiac development and disease. Nevertheless, detailed studies describing circRNA …

Relaxin-like peptide family exhibit differential expression patterns in various types of cancers
and play a role in cancer development. This family participates in tumorigenic processes …

Tissue nonspecific alkaline phosphatase (TNAP) is expressed widely in different tissues,
modulating functions of metabolism and inflammation. However, the effect of TNAP on …

Heart failure (HF) is a leading cause of morbidity and mortality particularly in older adults
and patients with multiple metabolic comorbidities. Heart failure with preserved ejection …

Bone morphogenetic protein 10 (BMP10) is a cardiac peptide growth factor belonging to the
transforming growth factor β superfamily that critically controls cardiovascular development …

Background The occurrence of pathological cardiac fibrosis is attributed to tissue hypoxia.
Circular RNAs play significant regulatory roles in multiple cardiovascular diseases and are …

Myocardial fibrosis is implicated as a leading risk factor for heart failure, arrhythmia, and
sudden death after cardiac injury, as the excessive interstitial extracellular matrix impedes …

The risk of osteoporosis is increased in rheumatoid arthritis (RA). Anti‐tumor necrosis factor
(TNF) therapy has markedly improved the outcomes of RA patients but does not improve …

ABSTRACT β-Adrenergic receptors (β-ARs) are expressed on the membranes of various
cell types, and their activation affects body water balance by modulating renal sodium and …