Stealthy microbes: How Neisseria gonorrhoeae hijacks bulwarked iron during infection
JL Stoudenmire, AN Greenawalt… - Frontiers in Cellular and …, 2022 - frontiersin.org
Transition metals are essential for metalloprotein function among all domains of life.
Humans utilize nutritional immunity to limit bacterial infections, employing metalloproteins …
Humans utilize nutritional immunity to limit bacterial infections, employing metalloproteins …
Glässer's disease
Glässer's disease occurs in swine populations around the world irrespective of health status,
and outbreaks of this economically significant disease may be linked to stress‐associated …
and outbreaks of this economically significant disease may be linked to stress‐associated …
Point mutations in TbpA abrogate human transferrin binding in Neisseria gonorrhoeae
AN Greenawalt, J Stoudenmire, K Lundquist… - Infection and …, 2022 - Am Soc Microbiol
TonB-dependent transporters (TDTs) are essential proteins for metal acquisition, an
important step in the growth and pathogenesis of many pathogens, including Neisseria …
important step in the growth and pathogenesis of many pathogens, including Neisseria …
Mutagenesis of the Loop 3 α-Helix of Neisseria gonorrhoeae TdfJ Inhibits S100A7 Binding and Utilization
SA Maurakis, JL Stoudenmire, JK Rymer, WJ Chazin… - Mbio, 2022 - Am Soc Microbiol
Neisseria gonorrhoeae causes the sexually transmitted infection (STI) gonorrhea, which
afflicts over 80 million people each year. No vaccine is available to prevent gonorrhea. The …
afflicts over 80 million people each year. No vaccine is available to prevent gonorrhea. The …
New insights about functional and cross-reactive properties of antibodies generated against recombinant TbpBs of Haemophilus parasuis
BM Barasuol, JA Guizzo, JE Fegan… - Scientific Reports, 2017 - nature.com
Vaccines have become fundamental in the control and elimination of Glässer Disease, a
systemic disease of pigs caused by Haemophilus parasuis. The classic vaccines available …
systemic disease of pigs caused by Haemophilus parasuis. The classic vaccines available …
The amino acid selected for generating mutant TbpB antigens defective in binding transferrin can compromise the in vivo protective capacity
JA Guizzo, S Chaudhuri, SR Prigol, R Yu, CC Dazzi… - Scientific Reports, 2018 - nature.com
Haemophilus parasuis is the causative agent of the Glässer's disease (GD), one of the most
important bacterial diseases that affect young pigs worldwide. GD prevention based on …
important bacterial diseases that affect young pigs worldwide. GD prevention based on …
Deletion of two-component system QseBC weakened virulence of Glaesserella parasuis in a murine acute infection model and adhesion to host cells
X Yan, K Dai, C Gu, Z Yu, M He, W Xiao, M Zhao, L He - PeerJ, 2022 - peerj.com
The widespread two-component system (TCS), QseBC, involves vital virulence regulators in
Enterobacteriaceae and Pasteurellaceae. Here we studied the function of QseBC in …
Enterobacteriaceae and Pasteurellaceae. Here we studied the function of QseBC in …
Investigating the importance of selected surface-exposed loops in HpuB for hemoglobin binding and utilization by Neisseria gonorrhoeae
OA Awate, D Ng, JL Stoudenmire, TF Moraes… - Infection and …, 2024 - Am Soc Microbiol
Neisseria gonorrhoeae is the etiological agent of the sexually transmitted infection
gonorrhea. The pathogen is a global health challenge since no protective immunity results …
gonorrhea. The pathogen is a global health challenge since no protective immunity results …
TbpB-based oral mucosal vaccine provides heterologous protection against Glässer's disease caused by different serovars of Spanish field isolates of Glaesserella …
A González-Fernández, O Mencía-Ares… - Porcine Health …, 2024 - Springer
Background Glaesserella parasuis (G. parasuis) is the primary agent of Glässer's disease,
significantly affecting nursery and early fattening piglets. Current prophylactic measures …
significantly affecting nursery and early fattening piglets. Current prophylactic measures …
Immunogenic characterization of vaccines based on Haemophilus parasuis Nagasaki strain, OmpP2, OmpP5 and OmpD15, in colostrum-deprived pigs experimentally …
Á Álvarez-Estrada, S Martínez-Martínez… - Research in veterinary …, 2018 - Elsevier
Three recombinant outer membrane proteins (rOmps) from the Haemophilus parasuis
Nagasaki strain (serovar 5 reference strain), rOmpP2, rOmpP5 and rOmpD15, which have …
Nagasaki strain (serovar 5 reference strain), rOmpP2, rOmpP5 and rOmpD15, which have …