Assessment of cardiovascular disease risk: a 2022 update

E Goldsborough, N Osuji… - … and Metabolism Clinics, 2022 - endo.theclinics.com
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, with
atherosclerotic cardiovascular disease (ASCVD) being the dominant cause of total CVD …

Cardiovascular disease and thrombosis in HIV infection

MV Perkins, SB Joseph, DP Dittmer… - … , and vascular biology, 2023 - Am Heart Assoc
HIV infection has transitioned from an acute, fatal disease to a chronic one managed by
antiretroviral therapy. Thus, the aging population of people living with HIV (PLWH) continues …

Association between immune checkpoint inhibitors with cardiovascular events and atherosclerotic plaque

ZD Drobni, RM Alvi, J Taron, A Zafar, SP Murphy… - Circulation, 2020 - Am Heart Assoc
Background: Immune checkpoint inhibitors (ICIs) treat an expanding range of cancers.
Consistent basic data suggest that these same checkpoints are critical negative regulators of …

HIV is associated with an increased risk of age-related clonal hematopoiesis among older adults

NJ Dharan, P Yeh, M Bloch, MM Yeung, D Baker… - Nature medicine, 2021 - nature.com
People with human immunodeficiency virus (HIV) have higher rates of certain comorbidities,
particularly cardiovascular disease and cancer, than people without HIV,,,–. In view of …

[HTML][HTML] Human immunodeficiency virus and clonal hematopoiesis

SC Vorri, I Christodoulou, S Karanika, T Karantanos - Cells, 2023 - mdpi.com
The evolution of antiretroviral therapies (ART) has tremendously improved the life
expectancy of people living with human immunodeficiency virus (HIV)(PLWH), which is …

Evolocumab in HIV-infected patients with dyslipidemia: primary results of the randomized, double-blind BEIJERINCK study

F Boccara, PN Kumar, B Caramelli, A Calmy… - Journal of the American …, 2020 - jacc.org
Background People living with human immunodeficiency virus (PLHIV) are at increased risk
of atherosclerotic cardiovascular disease (ASCVD) and are prone to statin-related adverse …

Distinct Gut Microbiota Signatures Associated With Progression of Atherosclerosis in People Living With Human Immunodeficiency Virus

M Masiá, JA García, J García-Abellán… - The Journal of …, 2024 - academic.oup.com
Background The relationship of microbiota composition dynamics and the progression of
subclinical atherosclerosis in people with human immunodeficiency virus (PWH) remains …

Hypertension and cardiovascular disease risk among individuals with versus without HIV

M Siddiqui, L Hannon, Z Wang, J Blair, S Oparil… - …, 2023 - Am Heart Assoc
Background: A high proportion of individuals with HIV have hypertension, and the incidence
of cardiovascular disease (CVD) is high in individuals with HIV. Methods: We determined if …

Sex modulates the association between inflammation and coronary atherosclerosis among older Ugandan adults with and without HIV

SS Shakil, TM Temu, C Kityo, R Nazzinda, G Erem… - Aids, 2023 - journals.lww.com
Objective: Inflammation is key in the pathogenesis of atherosclerotic coronary artery disease
(CAD). Distinct sex-specific inflammatory mechanisms may contribute to CAD in sub …

HIV infection and long‐term residual cardiovascular risk after acute coronary syndrome

F Boccara, M Mary‐Krause, V Potard… - Journal of the …, 2020 - Am Heart Assoc
Background It is unclear whether HIV infection affects the long‐term prognosis after an acute
coronary syndrome (ACS). The objective of the current study was to compare rates of major …