[HTML][HTML] 21-gene assay to inform chemotherapy benefit in node-positive breast cancer

K Kalinsky, WE Barlow, JR Gralow… - … England Journal of …, 2021 - Mass Medical Soc
Background The recurrence score based on the 21-gene breast-cancer assay has been
clinically useful in predicting a chemotherapy benefit in hormone-receptor–positive, human …

Oncotype DX Breast Recurrence Score®: A Review of its Use in Early-Stage Breast Cancer

YY Syed - Molecular diagnosis & therapy, 2020 - Springer
Abstract Oncotype DX Breast Recurrence Score® is a 21-gene prognostic and predictive
assay indicated for use in patients with hormone receptor-positive, human epidermal growth …

Is radiomic MRI a feasible alternative to OncotypeDX® recurrence score testing? A systematic review and meta-analysis

MG Davey, MS Davey, ÉJ Ryan, MR Boland… - BJS open, 2021 - academic.oup.com
Background OncotypeDX® recurrence score (RS) aids therapeutic decision-making in
oestrogen-receptor-positive (ER+) breast cancer. Radiomics is an evolving field that aims to …

Evaluation oncotype DX® 21‐gene recurrence score and clinicopathological parameters: a single institutional experience

A Lashen, MS Toss, W Fadhil, G Oni… - …, 2023 - Wiley Online Library
Aims Oncotype DX recurrence score (RS) is a clinically validated assay, which predicts the
likelihood of disease recurrence in oestrogen receptor‐positive/HER2‐negative …

Radiogenomic signatures of oncotype DX recurrence score enable prediction of survival in estrogen receptor–positive breast cancer: A multicohort study

M Fan, Y Cui, C You, L Liu, Y Gu, W Peng, Q Bai… - Radiology, 2022 - pubs.rsna.org
Background Radiogenomics explores the association between imaging features and
genomic assays to uncover relevant prognostic features; however, the prognostic …

Propensity score analysis of the prognostic value of genomic assays for breast cancer in diverse populations using the National Cancer Data Base

A Ibraheem, OI Olopade, D Huo - Cancer, 2020 - Wiley Online Library
Background Genomic assays such as Oncotype Dx (ODX) and MammaPrint are used for risk‐
adapted treatment decisions among patients with early breast cancer. However, to the …

The impact of age and nodal status on variations in oncotype DX testing and adjuvant treatment

K Iles, ML Roberson, P Spanheimer, K Gallagher… - NPJ Breast …, 2022 - nature.com
Oncotype DX (ODX) recurrence score (RS) is a validated tool to guide the use of adjuvant
chemotherapy (AC) in hormone receptor+/HER2-breast cancer. In this analysis, we examine …

Survival results according to Oncotype Dx recurrence score in patients with hormone receptor positive HER-2 negative early-stage breast cancer: first multicenter …

Ç Ünal, T Özmen, Ç Ordu, KN Pilanci, AS İlgün… - Frontiers in …, 2023 - frontiersin.org
Background The Oncotype Dx recurrence score (ODx-RS) guides the adjuvant
chemotherapy decision-making process for patients with early-stage hormone receptor …

Ten-year clinical outcomes in N0 ER+ breast cancer patients with Recurrence Score-guided therapy

SM Stemmer, M Steiner, S Rizel, N Ben-Baruch… - NPJ Breast …, 2019 - nature.com
Abstract The 21-gene Recurrence Score (RS) assay is a validated prognosticator/predictor
of chemotherapy (CT) benefit in early-stage estrogen receptor (ER)-positive breast cancer …

The 21-gene recurrence score in node-positive, hormone receptor-positive, HER2-negative breast cancer: a cautionary tale from an NCDB analysis

R Weiser, W Haque, E Polychronopoulou… - Breast Cancer Research …, 2021 - Springer
Purpose The 21-gene recurrence score assay (RS) has not been prospectively validated to
predict adjuvant chemotherapy benefit in hormone receptor-positive (HR+), HER2-negative …