T cells and natural killer (NK) cells have complementary roles in tumor immunity, and dual T
cell and NK cell attack thus offers opportunities to deepen the impact of immunotherapy …

Natural killer (NK) cells are critical effectors of antiviral immunity. Researchers have
therefore sought to characterize the NK cell response to coronavirus disease 2019 (COVID …

The immune system can eliminate tumors, but checkpoints enable immune escape. Here,
we identify immune evasion mechanisms using genome-scale in vivo CRISPR screens …

Abstract Human immunodeficiency virus 1 (HIV-1) reservoir cells persist lifelong despite
antiretroviral treatment, but may be vulnerable to host immune responses that could be …

Natural killer (NK) cells are innate immune cells that show strong cytolytic function against
physiologically stressed cells such as tumor cells and virus-infected cells. NK cells show a …

Allogeneic chimeric antigen receptor (CAR)-T cells hold great promise for expanding the
accessibility of CAR-T therapy, whereas the risks of allograft rejection have hampered its …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA generally becomes
undetectable in upper airways after a few days or weeks postinfection. Here we used a …

Cells of the innate immunity play an important role in tumor immunotherapy. Thus, NK cells
can control tumor growth and metastatic spread. Thanks to their strong cytolytic activity …

In recent decades, immune checkpoint blockade and chimeric antigen receptor T cell (CAR-
T) therapy are two milestone achievements in clinical immunotherapy. However, both show …

In an ongoing, open-label, single-arm phase II study (NCT02927301), 181 patients with
untreated, resectable, stage IB–IIIB non-small cell lung cancer received two doses of …