Among other legal regulations, the Note for Guidance on Allergen Products
CPMP/BWP/243/96 released by the European Medicines Agency provides regulatory …

The vasodilator-stimulated phosphoprotein (VASP) is a major substrate for cyclic nucleotide-
dependent kinases in platelets and other cardiovascular cells. It promotes actin nucleation …

In epithelial cells, α-, β-, and γ-catenin are involved in linking the peripheral microfilament
belt to the transmembrane protein E-cadherin. α-Catenin exhibits sequence homologies …

Type I allergy, a hypersensitivity disease affecting almost 20% of the population worldwide,
is based on the IgE recognition of otherwise harmless antigens (ie, allergens). Allergen …

Spinal muscular atrophy (SMA) is an autosomal recessive disorder characterized by the loss
of α-motoneurons in the spinal cord followed by atrophy of skeletal muscles. SMA …

Background: The profilins are a group of ubiquitous actin monomer binding proteins that are
responsible for regulating the normal distribution of filamentous actin networks in eukaryotic …

Allergic inflammation is based on the cross-linking of mast cell and basophil-bound IgE Abs
and requires at least two binding sites for IgE on allergens, which are difficult to characterize …

Background Profilins are highly cross-reactive allergens which bind IgE antibodies of almost
20% of plant-allergic patients. This study is aimed at investigating cross-reactivity of melon …

The spatial and temporal activity of the actin cytoskeleton is precisely regulated during cell
motility by several microfilament-associated proteins of which profilin plays an essential role …

Profilins, regulators of cytoplasmic actin dynamics, also bind to several nuclear proteins but
the significance of these interactions is mostly unclear. Here, we describe a novel Myb …