The clinical presentation and the pathological processes underlying Alzheimer's disease
(AD) can be very heterogeneous in severity, location, and composition including the amount …

African American/Black adults are twice as likely to have Alzheimer's disease (AD)
compared to non-Hispanic White adults. Genetics partially contributes to this disparity in AD …

(Genome-wide Association Studies) GWAS have identified∼ 42 late-onset Alzheimer's
disease (LOAD)-associated loci, each of which contains multiple single nucleotide …

Alzheimer's disease (AD) is a complex genetic disorder. To date, published data have
reported conflicting results on the role of CD33 rs3865444 polymorphism in AD. The present …

The increased production of the 42 aminoacids long beta-amyloid (Aβ42) peptide has been
established as a causal mechanism of the familial early onset Alzheimer's disease (AD). In …

Background Genetic studies have primarily been conducted in European ancestry
populations, identifying dozens of loci associated with late-onset Alzheimer's disease (AD) …

Alzheimer's disease (AD) is on the rise worldwide. Generally, AD is considered
neurodegenerative when the production and clearance of amyloid-β (Aβ) are imbalanced …

Objective Parkinson's disease (PD) represents the multisystem illness involving
immunological and neuroinflammatory dysfunction. The present work focused on evaluating …

Clusterin (CLU) is considered one of the most important roles for pathogenesis of
Alzheimer's Disease (AD). The early genome-wide association studies (GWAS) identified …

Alzheimer's disease (AD) and frontotemporal dementia (FTD) are neurodegenerative
disorders that result in a significant burden to both patients and caregivers. By 2050, the …