Epigallocatechin-gallate attenuates rapamycin exacerbated high fat diet-induced autophagy, hormonal dysregulation, testicular and brain oxidative stress, and …

CC Onyekweli, B Ben-Azu, OM Oyovwi… - Food and Chemical …, 2024 - Elsevier
This study investigated whether epigallocatechin-gallate (EGCG) could counteract the
detrimental effects of high-fat diet (HFD)-induced obesity in rats exposed to rapamycin …

D-Ribose-L-Cysteine Attenuated Polychlorinated Biphenyls Mediated Neuroendocrine-Transmembrane Ionic Pump ATPase Disruption and Peroxynitrite Formation in …

OM Obukohwo, TP Edesiri, BA Benneth, E Victor… - Trends in …, 2023 - tis.wu.ac.th
The very hazardous and persistent aquatic pollutants known as polychlorinated biphenyls
(PCBs) are known to bioaccumulate in a range of marine mammals. Human and animal …

[HTML][HTML] Arjunolic acid reverses fluoxetine-induced alterations in testicular steroidogenic enzymes and membrane bound ionic pump imbalance through suppression …

EO Lynda, NE Kingsley, OM Obukohwo… - JBRA Assisted …, 2024 - ncbi.nlm.nih.gov
Objective The impact of the anti-depressant therapy on gonadal function has been
recognized and discussed over the years. However, data to supplement our understanding …

Taurine and N-acetylcysteine reverse reproductive and neuroendocrine dysfunctions in levetiracetam-treated epileptic male rats

E Victor, O Mega Obukohwo… - Egyptian Journal of …, 2023 - Taylor & Francis
Reproductive neuroendocrine dysfunction is becoming common among patients with
epilepsy, Notably, possible indication of taurine and N-acetylcysteine (NAC) in the …

[HTML][HTML] Lycopene supplement mitigates polystyrene microplastics (PS-MPs)-induced reproductive alteration in rats via modulation of steroidogenic enzymes …

OM Obukohwo, OA Abodunrin, OP Ejiro… - Kuwait Journal of …, 2024 - Elsevier
Increasing levels of polystyrene microplastics (PS-MPs) in the environment poses huge
global health threat. Prolonged exposure to PS-MPs results in both male and female …

[HTML][HTML] Cytotoxic Properties of Cyclophosphamide: A Focus on Its Mechanistic Impacts on Male Gonadal Functions

TG Olowe, MO Oyovwi, KE Nwangwa… - Journal of …, 2024 - xiahepublishing.com
Cyclophosphamide (CP) is a potent chemotherapeutic agent utilized in the treatment of
various types of cancer. However, in addition to its efficacy in combating cancer, CP also has …

[HTML][HTML] Modified rougan decoction attenuates hepatocyte apoptosis through ameliorating mitochondrial dysfunction by upregulated SIRT1/PGC-1α signaling pathway

W Wang, D Wu, J Ding, J Wang, J Meng, K Ming, S Li… - Poultry Science, 2023 - Elsevier
The modified rougan decoction (MRGD) compound formula has been proven a certain
ability to relieve lipopolysaccharide-enrofloxacin (LPS-ENR)-induced liver oxidant injury in …

N-acetyl cysteine and zinc sulphate ameliorated crude oil-induced hepatotoxicity in Wistar rats

O Ochuko, NA Obidike… - … Advanced Biology and …, 2023 - magnascientiapub.com
Even while crude oil offers many advantages, its toxic chemical composition has been
shown to negatively interfere with the body's ability to maintain homeostasis. This …

Therapeutic indication of caffeine and vitamin c on haematological profile in heparin, phenylhydrazine and aspirin induced haematological derangements in male …

O Okporu, JC Igweh, OO Mega - International Journal of Science and …, 2023 - ijsra.net
Background: Caffeine and Vitamin C, key component in foods and beverages, have been
investigated for potential haematological disease prevention. Aim: To lend credence to the …

[PDF][PDF] Journal of Chemical Health Risks

OM Obukohwo, OP Ejiro - researchgate.net
Polystyrene microplastics (PS-MPs) pose a significant scientific concern due to their
chemical makeup. Luteolin (LUT), a phytochemical-biological substance with anti-oxidative …