Cancer cells tune the signaling pathways to empower de novo synthesis of nucleotides

E Villa, ES Ali, U Sahu, I Ben-Sahra - Cancers, 2019 - mdpi.com
Cancer cells exhibit a dynamic metabolic landscape and require a sufficient supply of
nucleotides and other macromolecules to grow and proliferate. To meet the metabolic …

Biocompatibility of engineered nanoparticles for drug delivery

S Naahidi, M Jafari, F Edalat, K Raymond… - Journal of controlled …, 2013 - Elsevier
The rapid advancement of nanotechnology has raised the possibility of using engineered
nanoparticles that interact within biological environments for treatment of diseases …

Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer

LA Forsberg, C Rasi, N Malmqvist, H Davies… - Nature …, 2014 - nature.com
Incidence and mortality for sex-unspecific cancers are higher among men, a fact that is
largely unexplained,. Furthermore, age-related loss of chromosome Y (LOY) is frequent in …

Anti cancer effects of curcumin: cycle of life and death

G Sa, T Das - Cell division, 2008 - Springer
Increasing knowledge on the cell cycle deregulations in cancers has promoted the
introduction of phytochemicals, which can either modulate signaling pathways leading to …

Cancer stem cell immunology: key to understanding tumorigenesis and tumor immune escape?

VS Bruttel, J Wischhusen - Frontiers in immunology, 2014 - frontiersin.org
Cancer stem cell (CSC) biology and tumor immunology have shaped our understanding of
tumorigenesis. However, we still do not fully understand why tumors can be contained but …

The risk of malignancy in patients with IgG4-related disease: a systematic review and meta-analysis

T Yu, Y Wu, J Liu, Y Zhuang, X Jin, L Wang - Arthritis Research & Therapy, 2022 - Springer
Abstract Background The relationship between IgG4-related disease (IgG4-RD) and the risk
of malignancy is still controversial. This article focused on assessing the risk of cancer in …

High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epithelium

CW Huo, G Chew, P Hill, D Huang, W Ingman… - Breast Cancer …, 2015 - Springer
Introduction Mammographic density (MD), after adjustment for a women's age and body
mass index, is a strong and independent risk factor for breast cancer (BC). Although the BC …

[HTML][HTML] Prospective registry‐based observational cohort study of the long‐term risk of malignancies in renal transplant patients treated with mycophenolate mofetil

R Robson, JM Cecka, G Opelz, M Budde… - American Journal of …, 2005 - Elsevier
This large prospectively conducted observational cohort study examined the risk of
lymphoma and other malignancies with mycophenolate mofetil (MMF) in de novo renal …

Role of cell surface proteoglycans in cancer immunotherapy

NA Espinoza-Sánchez, M Götte - Seminars in cancer biology, 2020 - Elsevier
Over the past few decades, understanding how tumor cells evade the immune system and
their communication with their tumor microenvironment, has been the subject of intense …

Tumor immunoediting and immunosculpting pathways to cancer progression

JM Reiman, M Kmieciak, MH Manjili… - Seminars in cancer …, 2007 - Elsevier
Recent studies have suggested that a natural function of the immune system is to respond
and destroy aberrant, dysfunctional cells by a process called immunosurveillance. These …