The amyloid cascade hypothesis: an updated critical review
Results from recent clinical trials of antibodies that target amyloid-β (Aβ) for Alzheimer's
disease have created excitement and have been heralded as corroboration of the amyloid …
disease have created excitement and have been heralded as corroboration of the amyloid …
The gut microbiome in neurological disorders
JF Cryan, KJ O'Riordan, K Sandhu, V Peterson… - The Lancet …, 2020 - thelancet.com
Research into the role of the gut microbiome in modulating brain function has rapidly
increased over the past 10 years, albeit chiefly in animal models. Increasing clinical and …
increased over the past 10 years, albeit chiefly in animal models. Increasing clinical and …
[HTML][HTML] The microbiota-gut-brain axis
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
Pathogenesis and virulence of herpes simplex virus
S Zhu, A Viejo-Borbolla - Virulence, 2021 - Taylor & Francis
Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2
(HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital …
(HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital …
[HTML][HTML] Gut microbiota and dysbiosis in Alzheimer's disease: implications for pathogenesis and treatment
S Liu, J Gao, M Zhu, K Liu, HL Zhang - Molecular neurobiology, 2020 - Springer
Understanding how gut flora influences gut-brain communications has been the subject of
significant research over the past decade. The broadening of the term “microbiota-gut-brain …
significant research over the past decade. The broadening of the term “microbiota-gut-brain …
[HTML][HTML] History and progress of hypotheses and clinical trials for Alzheimer's disease
PP Liu, Y Xie, XY Meng, JS Kang - Signal transduction and targeted …, 2019 - nature.com
Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
memory loss along with neuropsychiatric symptoms and a decline in activities of daily life. Its …
memory loss along with neuropsychiatric symptoms and a decline in activities of daily life. Its …
COVID‐19 and dementia: Analyses of risk, disparity, and outcomes from electronic health records in the US
QQ Wang, PB Davis, ME Gurney… - Alzheimer's & Dementia, 2021 - Wiley Online Library
Introduction At present, there is limited data on the risks, disparity, and outcomes for COVID‐
19 in patients with dementia in the United States. Methods This is a retrospective case …
19 in patients with dementia in the United States. Methods This is a retrospective case …
[HTML][HTML] Brain-gut-microbiota axis in Alzheimer's disease
K Kowalski, A Mulak - Journal of neurogastroenterology and …, 2019 - ncbi.nlm.nih.gov
Disturbances along the brain-gut-microbiota axis may significantly contribute to the
pathogenesis of neurodegenerative disorders. Alzheimer's disease (AD) is the most frequent …
pathogenesis of neurodegenerative disorders. Alzheimer's disease (AD) is the most frequent …
[HTML][HTML] Impact of microbiota on central nervous system and neurological diseases: the gut-brain axis
Q Ma, C Xing, W Long, HY Wang, Q Liu… - Journal of …, 2019 - Springer
Abstract Development of central nervous system (CNS) is regulated by both intrinsic and
peripheral signals. Previous studies have suggested that environmental factors affect …
peripheral signals. Previous studies have suggested that environmental factors affect …
[HTML][HTML] Multiscale analysis of independent Alzheimer's cohorts finds disruption of molecular, genetic, and clinical networks by human herpesvirus
Investigators have long suspected that pathogenic microbes might contribute to the onset
and progression of Alzheimer's disease (AD) although definitive evidence has not been …
and progression of Alzheimer's disease (AD) although definitive evidence has not been …