Red blood cell metabolism in vivo and in vitro
Red blood cells (RBC) are the most abundant cell in the human body, with a central role in
oxygen transport and its delivery to tissues. However, omics technologies recently revealed …
oxygen transport and its delivery to tissues. However, omics technologies recently revealed …
Blood group genotyping
CM Westhoff - Blood, The Journal of the American Society of …, 2019 - ashpublications.org
Genomics is affecting all areas of medicine. In transfusion medicine, DNA-based genotyping
is being used as an alternative to serological antibody-based methods to determine blood …
is being used as an alternative to serological antibody-based methods to determine blood …
Genetic polymorphisms and expression of Rhesus blood group RHCE are associated with 2, 3-bisphosphoglycerate in humans at high altitude
Red blood cell (RBC) metabolic reprogramming upon exposure to high altitude contributes
to physiological human adaptations to hypoxia, a multifaceted process critical to health and …
to physiological human adaptations to hypoxia, a multifaceted process critical to health and …
[HTML][HTML] Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate …
Red blood cell (RBC) storage in the blood bank promotes the progressive accumulation of
metabolic alterations that may ultimately impact the erythrocyte capacity to cope with oxidant …
metabolic alterations that may ultimately impact the erythrocyte capacity to cope with oxidant …
Biological and genetic determinants of glycolysis: Phosphofructokinase isoforms boost energy status of stored red blood cells and transfusion outcomes
Mature red blood cells (RBCs) lack mitochondria and thus exclusively rely on glycolysis to
generate adenosine triphosphate (ATP) during aging in vivo or storage in blood banks …
generate adenosine triphosphate (ATP) during aging in vivo or storage in blood banks …
Effect of donor, component, and recipient characteristics on hemoglobin increments following red blood cell transfusion
NH Roubinian, C Plimier, JP Woo, C Lee… - Blood, The Journal …, 2019 - ashpublications.org
Significant research has focused individually on blood donors, product preparation and
storage, and optimal transfusion practice. To better understand the interplay between these …
storage, and optimal transfusion practice. To better understand the interplay between these …
Multiple-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage
Background The evolutionary pressure of endemic malaria and other erythrocytic pathogens
has shaped variation in genes encoding erythrocyte structural and functional proteins …
has shaped variation in genes encoding erythrocyte structural and functional proteins …
[HTML][HTML] The interactome of the N-terminus of band 3 regulates red blood cell metabolism and storage quality
A Issaian, A Hay, M Dzieciatkowska, D Roberti… - …, 2021 - ncbi.nlm.nih.gov
Abstract Band 3 (anion exchanger 1; AE1) is the most abundant membrane protein in red
blood cells, which in turn are the most abundant cells in the human body. A compelling …
blood cells, which in turn are the most abundant cells in the human body. A compelling …
Genome-wide metabolite quantitative trait loci analysis (mQTL) in red blood cells from volunteer blood donors
A Moore, MP Busch, K Dziewulska, RO Francis… - Journal of Biological …, 2022 - ASBMB
The red blood cell (RBC)-Omics study, part of the larger NHLBI-funded Recipient
Epidemiology and Donor Evaluation Study (REDS-III), aims to understand the genetic …
Epidemiology and Donor Evaluation Study (REDS-III), aims to understand the genetic …
Red blood cell storage: from genome to exposome towards personalized transfusion medicine
A D'Alessandro, EA Hod - Transfusion Medicine Reviews, 2023 - Elsevier
Over the last decade, the introduction of omics technologies–especially high-throughput
genomics and metabolomics–has contributed significantly to our understanding of the role of …
genomics and metabolomics–has contributed significantly to our understanding of the role of …