The definition of metabolic syndrome (MetS) has undergone several changes over the years
due to the difficulty in establishing universal criteria for it. Underlying the disorders related to …

As important metabolic substrates, branched-chain amino acids (BCAAs) and fatty acids
(FAs) participate in many significant physiological processes, such as mitochondrial …

The aims of the present article are to systematically review and meta-analyze the existing
evidence on: 1) differences in physical activity (PA), sedentary behavior (SB) …

Recent studies have shown the positive association between increased circulating BCAAs
(valine, leucine, and isoleucine) and insulin resistance (IR) in obese or diabetic patients …

Abstract Orosomucoid (ORM), or alpha-1-acid glycoprotein (AGP), is one of the acute-phase
proteins. It has a molecular weight of 37–54 kDa, low pI of 2.8–3.8, and is heavily …

Background Metabolic syndrome (MS) is a construct used to separate “healthy” from
“unhealthy” obese patients, and is a major risk factor for type 2 diabetes (T2D) and …

The aim of this work was to conduct a systematic review of human studies on metabolite/lipid
biomarkers of metabolic syndrome (MetS) and its components, and provide …

Obesity is a risk factor for the development of type 2 diabetes and cardiovascular disease.
However, it is now recognized that a subset of individuals have reduced cardiometabolic risk …

The clinical manifestations of overweight/obesity are heterogeneous and complex. In
contrast to metabolically unhealthy overweight/obese (MUO), a particular sub-group of …

Obesity rates among children are growing rapidly worldwide, placing massive pressure on
healthcare systems. Untargeted metabolomics can expand our understanding of the …