Frequently underestimated, encephalopathy or delirium are common neurological
manifestations associated with sepsis. Brain dysfunction occurs in up to 80% of cases and is …

Sepsis-associated encephalopathy (SAE) is a common complication caused by sepsis, and
is responsible for increased mortality and poor outcomes in septic patients. Neurological …

Bioavailable glutamine (Gln) is critical for metabolism, intestinal health, immune function,
and cell signaling. Routine measurement of serum Gln concentrations could facilitate …

Human microbiota produces metabolites that may enter the bloodstream and exert systemic
influence on various functions including mitochondrial. Mitochondria are not only a target for …

Cell‐free protein synthesis (CFPS) is a versatile biotechnology platform enabling a broad
range of applications including clinical diagnostics, large‐scale production of officinal …

Sepsis is characterised by dysregulated immune responses to infection, leading to multi-
organ dysfunction and high rates of mortality. With increasing survival rates in recent years …

Background: Circulatory shock is a life-threatening disorder that is associated with high
mortality, with a state of systemic and tissue hypoperfusion that can lead to organ failure …

A sepse é caracterizada pela produção excessiva de mediadores inflamatórios, que ao
afetar o sistema nervoso central (SNC), gera danos cerebrais e comprometimento cognitivo …

Methods: In 8 sheep, peritonitis was induced by injection of feces into the abdominal cavity.
At the onset of septic shock (mean arterial pressure, MAp< 65 mmHg, unresponsive to fluid …

Therapeutic proteins have become a cornerstone of modern medicine since the FDA
approval of recombinant human insulin in 1982. Likewise, biosensors transform chemical …