The rapid emergence of antifungal-resistant human-pathogenic fungi
SR Lockhart, A Chowdhary, JAW Gold - Nature Reviews Microbiology, 2023 - nature.com
During recent decades, the emergence of pathogenic fungi has posed an increasing public
health threat, particularly given the limited number of antifungal drugs available to treat …
health threat, particularly given the limited number of antifungal drugs available to treat …
Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …
globe. Candida species are among the most common causes of invasive mycotic disease …
Fluconazole resistance in Candida species: a current perspective
EL Berkow, SR Lockhart - Infection and drug resistance, 2017 - Taylor & Francis
Candida albicans and the emerging non-albicans Candida spp. have significant clinical
relevance among many patient populations. Current treatment guidelines include …
relevance among many patient populations. Current treatment guidelines include …
Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species
Within the limited antifungal armamentarium, the azole antifungals are the most frequent
class used to treat Candida infections. Azole antifungals such as fluconazole are often …
class used to treat Candida infections. Azole antifungals such as fluconazole are often …
Antifungal drug resistance among Candida species: mechanisms and clinical impact
The epidemiology of Candida infections has changed in recent years. Although Candida
albicans is still the main cause of invasive candidiasis in most clinical settings, a substantial …
albicans is still the main cause of invasive candidiasis in most clinical settings, a substantial …
Evolutionary Emergence of Drug Resistance in Candida Opportunistic Pathogens
E Ksiezopolska, T Gabaldón - Genes, 2018 - mdpi.com
Fungal infections, such as candidiasis caused by Candida, pose a problem of growing
medical concern. In developed countries, the incidence of Candida infections is increasing …
medical concern. In developed countries, the incidence of Candida infections is increasing …
Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance
MA Ghannoum, LB Rice - Clinical microbiology reviews, 1999 - Am Soc Microbiol
The increased use of antibacterial and antifungal agents in recent years has resulted in the
development of resistance to these drugs. The significant clinical implication of resistance …
development of resistance to these drugs. The significant clinical implication of resistance …
Fungal–metal interactions: A review of toxicity and homeostasis
JR Robinson, OS Isikhuemhen, FN Anike - Journal of Fungi, 2021 - mdpi.com
Metal nanoparticles used as antifungals have increased the occurrence of fungal–metal
interactions. However, there is a lack of knowledge about how these interactions cause …
interactions. However, there is a lack of knowledge about how these interactions cause …
Nosocomial fungal infections: epidemiology, diagnosis, and treatment
J Perlroth, B Choi, B Spellberg - Medical mycology, 2007 - academic.oup.com
Invasive fungal infections are increasingly common in the nosocomial setting. Furthermore,
because risk factors for these infections continue to increase in frequency, it is likely that …
because risk factors for these infections continue to increase in frequency, it is likely that …
Efflux-mediated antifungal drug resistance
Fungi cause serious infections in the immunocompromised and debilitated, and the
incidence of invasive mycoses has increased significantly over the last 3 decades. Slow …
incidence of invasive mycoses has increased significantly over the last 3 decades. Slow …