Atherosclerosis can be regarded as a chronic inflammatory state, in which macrophages
play different and important roles. Phagocytic proinflammatory cells populate growing …

Lipid accumulation in the arterial wall is a crucial event in the development of atherosclerotic
lesions. Circulating low-density lipoprotein (LDL) is the major source of lipids that …

Oxysterols are present in human atherosclerotic plaque and are suggested to play an active
role in plaque development. Moreover, the oxysterol: cholesterol ratio in plaque is much …

Sialic acid (SA), N‐acetylated derivatives of neuraminic acid, play a central role in the
biomedical functioning of humans. The normal range of total sialic acid (TSA) level in …

A review of relevant literature on biological activities of oxysterols (OS) and cholesterol is
presented. The data clearly demonstrate manifold biological activities, often detrimental, for …

Membrane cholesterol is essential for cell membrane properties, just as serum cholesterol is
important for the transport of molecules between organs. This review focuses on cholesterol …

Chronic inflammation is a pathogenic mechanism of many diseases causing up to 80% of
morbidity and mortality in developed countries. Despite many discoveries made in the field …

Protein glycosylation is a post-translational modification consisting in the enzymatic
attachment of carbohydrate chains to specific residues of the protein sequence. Several …

Background: Atherosclerosis is a chronic inflammatory condition that affects different arteries
in the human body and often leads to severe neurological complications, such as stroke and …

In atherosclerosis; blood low-density lipoproteins (LDL) are subjected to multiple enzymatic
and non-enzymatic modifications that increase their atherogenicity and induce …