Determination of bile salt critical micellization concentration on the road to drug discovery
With the discovery of the bile acid (BA)-activated nuclear and membrane receptors, the role
of BAs as signalling molecules in important paracrine and endocrine networks has been …
of BAs as signalling molecules in important paracrine and endocrine networks has been …
A molecular image-based novel quantitative structure-activity relationship approach, deepsnap-deep learning and machine learning
Y Matsuzaka, Y Uesawa - Current issues in molecular biology, 2021 - mdpi.com
The quantitative structure-activity relationship (QSAR) approach has been used in numerous
chemical compounds as in silico computational assessment for a long time. Further, owing …
chemical compounds as in silico computational assessment for a long time. Further, owing …
Mixed micelles of sodium cholate and sodium dodecylsulphate 1: 1 binary mixture at different temperatures–experimental and theoretical investigations
Micellisation process for sodium dodecyl sulphate and sodium cholate in 1∶ 1 molar ratio
was investigated in a combined approach, including several experimental methods and …
was investigated in a combined approach, including several experimental methods and …
Hologram QSAR study on the critical micelle concentration of Gemini surfactants
L Jiao, Y Wang, L Qu, Z Xue, Y Ge, H Liu, B Lei… - Colloids and Surfaces A …, 2020 - Elsevier
A quantitative structure-property relationship (QSPR) study on the critical micelle
concentration (CMC) of 120 Gemini surfactants was performed with hologram quantitative …
concentration (CMC) of 120 Gemini surfactants was performed with hologram quantitative …
Determination of number-average aggregation numbers of bile salts micelles with a special emphasis on their oxo derivatives—The effect of the steroid skeleton
M Poša, A Sebenji - Biochimica et Biophysica Acta (BBA)-General Subjects, 2014 - Elsevier
Background The special geometry of the steroid skeleton causes that bile acid anions, in
contrast to aliphatic amphiphiles, form micelles with a small aggregation number. Methods …
contrast to aliphatic amphiphiles, form micelles with a small aggregation number. Methods …
Heuman indices of hydrophobicity of bile acids and their comparison with a newly developed and conventional molecular descriptors
M Poša - Biochimie, 2014 - Elsevier
Bile salts (BSs), in addition to their physiological role in the digestion of lipids in vertebrates,
are also of significant importance in biomedical investigations. For predicting biological …
are also of significant importance in biomedical investigations. For predicting biological …
Mixed micelles of sodium salts of bile acids and Tween 40: effect of the steroid skeleton on the coefficient of interaction in mixed micelles
Salts of bile acids are steroid amphiphilic compounds which form micelles consisting of 2–
12 monomer units. In nature, the formation of mixed micelles with phospholipids (gall …
12 monomer units. In nature, the formation of mixed micelles with phospholipids (gall …
Physico-chemical properties of bile salt-Tween 80 mixed micelles in the viewpoint of regular solution theory
In this work mixed micelles of Na salts of bile acids and Tween 80 are studied. In the
experiment, number and orientation of OH and oxo groups in the steroid skeleton of bile acid …
experiment, number and orientation of OH and oxo groups in the steroid skeleton of bile acid …
Physicochemical investigation of novel biodegradable dicationic ester bonded m-E2-m gemini surfactants with bile salts: insights from surface tension, dynamic light …
Due to the potential use of bile salts in drug delivery, the mixed micellar, microstrutural and
mixed monolayer investigations of three biodegradable diester bearing cleavable gemini …
mixed monolayer investigations of three biodegradable diester bearing cleavable gemini …
CMC of diverse Gemini surfactants modelling using a hybrid approach combining SVR-DA
M Laidi, HA Abdallah, C Si-Moussa… - Chemical Industry …, 2021 - doiserbia.nb.rs
Quantitative structure-property relationship (QSPR) technique provides a suitable tool to
predict the critical micelle concentration (CMC) of Gemini surfactants from their structure …
predict the critical micelle concentration (CMC) of Gemini surfactants from their structure …