Frozen shoulder
NL Millar, A Meakins, F Struyf, E Willmore… - Nature reviews Disease …, 2022 - nature.com
Frozen shoulder is a common debilitating disorder characterized by shoulder pain and
progressive loss of shoulder movement. Frozen shoulder is frequently associated with other …
progressive loss of shoulder movement. Frozen shoulder is frequently associated with other …
Roles of cancer-associated fibroblasts (CAFs) in anti-PD-1/PD-L1 immunotherapy for solid cancers
L Pei, Y Liu, L Liu, S Gao, X Gao, Y Feng, Z Sun… - Molecular cancer, 2023 - Springer
In recent years, breakthroughs have been made in tumor immunotherapy. However, tumor
immunotherapy, particularly anti-PD-1/PD-L1 immune checkpoint inhibitors, is effective in …
immunotherapy, particularly anti-PD-1/PD-L1 immune checkpoint inhibitors, is effective in …
TGF-β-mediated epithelial-mesenchymal transition and cancer metastasis
Transforming growth factor β (TGF-β) is a secreted cytokine that regulates cell proliferation,
migration, and the differentiation of a plethora of different cell types. Consistent with these …
migration, and the differentiation of a plethora of different cell types. Consistent with these …
From NAFLD to MAFLD: implications of a premature change in terminology
Despite the substantial gains in our understanding of NAFLD/NASH over the past 2
decades, there has been some dissatisfaction with the terminology “non‐alcoholic” which …
decades, there has been some dissatisfaction with the terminology “non‐alcoholic” which …
The extracellular matrix in tumor progression and metastasis
JA Eble, S Niland - Clinical & experimental metastasis, 2019 - Springer
The extracellular matrix (ECM) constitutes the scaffold of tissues and organs. It is a complex
network of extracellular proteins, proteoglycans and glycoproteins, which form …
network of extracellular proteins, proteoglycans and glycoproteins, which form …
TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure
A Chakravarthy, L Khan, NP Bensler, P Bose… - Nature …, 2018 - nature.com
The extracellular matrix (ECM) is a key determinant of cancer progression and prognosis.
Here we report findings from one of the largest pan-cancer analyses of ECM gene …
Here we report findings from one of the largest pan-cancer analyses of ECM gene …
Transforming growth factor-β-induced cell plasticity in liver fibrosis and hepatocarcinogenesis
I Fabregat, D Caballero-Díaz - Frontiers in oncology, 2018 - frontiersin.org
The Transforming Growth Factor-beta (TGF-β) family plays relevant roles in the regulation of
different cellular processes that are essential for tissue and organ homeostasis. In the case …
different cellular processes that are essential for tissue and organ homeostasis. In the case …
YAP/TAZ signaling as a molecular link between fibrosis and cancer
S Noguchi, A Saito, T Nagase - International journal of molecular sciences, 2018 - mdpi.com
Tissue fibrosis is a pathological condition that is associated with impaired epithelial repair
and excessive deposition of extracellular matrix (ECM). Fibrotic lesions increase the risk of …
and excessive deposition of extracellular matrix (ECM). Fibrotic lesions increase the risk of …
Transforming growth factor-β signaling in fibrotic diseases and cancer-associated fibroblasts
X Shi, CD Young, H Zhou, XJ Wang - Biomolecules, 2020 - mdpi.com
Transforming growth factor-β (TGF-β) signaling is essential in embryo development and
maintaining normal homeostasis. Extensive evidence shows that TGF-β activation acts on …
maintaining normal homeostasis. Extensive evidence shows that TGF-β activation acts on …
Heparanase and the hallmarks of cancer
KM Jayatilleke, MD Hulett - Journal of Translational Medicine, 2020 - Springer
Heparanase is the only mammalian enzyme that cleaves heparan sulphate, an important
component of the extracellular matrix. This leads to the remodelling of the extracellular …
component of the extracellular matrix. This leads to the remodelling of the extracellular …