Retinoic acid signaling pathways

NB Ghyselinck, G Duester - Development, 2019 - journals.biologists.com
Retinoic acid (RA), a metabolite of retinol (vitamin A), functions as a ligand for nuclear RA
receptors (RARs) that regulate development of chordate animals. RA-RARs can activate or …

Retinoic acid signalling during development

M Rhinn, P Dollé - Development, 2012 - journals.biologists.com
Retinoic acid (RA) is a vitamin A-derived, non-peptidic, small lipophilic molecule that acts as
ligand for nuclear RA receptors (RARs), converting them from transcriptional repressors to …

[HTML][HTML] Blood transcriptomic signatures associated with molecular changes in the brain and clinical outcomes in Parkinson's disease

K Irmady, CR Hale, R Qadri, J Fak, S Simelane… - Nature …, 2023 - nature.com
The ability to use blood to predict the outcomes of Parkinson's disease, including disease
progression and cognitive and motor complications, would be of significant clinical value …

Retinoic acid receptors: from molecular mechanisms to cancer therapy

A Di Masi, L Leboffe, E De Marinis, F Pagano… - Molecular aspects of …, 2015 - Elsevier
Retinoic acid (RA), the major bioactive metabolite of retinol or vitamin A, induces a spectrum
of pleiotropic effects in cell growth and differentiation that are relevant for embryonic …

Mechanistic aspects of carotenoid health benefits–where are we now?

T Bohn, ML Bonet, P Borel, J Keijer… - Nutrition Research …, 2021 - cambridge.org
Dietary intake and tissue levels of carotenoids have been associated with a reduced risk of
several chronic diseases, including cardiovascular diseases, type 2 diabetes, obesity, brain …

Neurobiology of the structure of personality: Dopamine, facilitation of incentive motivation, and extraversion

RA Depue, PF Collins - Behavioral and brain sciences, 1999 - cambridge.org
Extraversion has two central characteristics:(1) interpersonal engagement, which consists of
affiliation (enjoying and valuing close interpersonal bonds, being warm and affectionate) …

Overview of retinoid metabolism and function

R Blomhoff, HK Blomhoff - Journal of neurobiology, 2006 - Wiley Online Library
Retinoids (vitamin A) are crucial for most forms of life. In chordates, they have important roles
in the developing nervous system and notochord and many other embryonic structures, as …

[图书][B] What's wrong with my mouse?: behavioral phenotyping of transgenic and knockout mice

JN Crawley - 2007 - books.google.com
Dr. Jacqueline N. Crawley, author of the First and Second Editions of What's Wrong with My
Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice, continues to field calls …

Is obesity an inflammatory condition?

UN Das - Nutrition, 2001 - Elsevier
Obesity may be a low-grade systemic inflammatory disease. Overweight and obese children
and adults have elevated serum levels of C-reactive protein, interleukin-6, tumor necrosis …

Structure and function of dopamine receptors

D Vallone, R Picetti, E Borrelli - Neuroscience & biobehavioral reviews, 2000 - Elsevier
Dopamine (DA) is the most abundant catecholamine in the brain. The involvement and
importance of DA as a neurotransmitter in the regulation of different physiological functions …