Detection and analysis of chiral molecules as disease biomarkers
The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …
Reactive oxygen nano-generators for cancer therapy
Reactive oxygen species (ROS) play a vital role in the biological process. Interestingly,
based on the concentration of the ROS level, they can be beneficial or detrimental to tumor …
based on the concentration of the ROS level, they can be beneficial or detrimental to tumor …
D-cysteine is an endogenous regulator of neural progenitor cell dynamics in the mammalian brain
ER Semenza, MM Harraz… - Proceedings of the …, 2021 - National Acad Sciences
d-amino acids are increasingly recognized as important signaling molecules in the
mammalian central nervous system. However, the d-stereoisomer of the amino acid with the …
mammalian central nervous system. However, the d-stereoisomer of the amino acid with the …
A guide to genetically encoded tools for the study of H2O2
DD Smolyarova, OV Podgorny, DS Bilan… - The FEBS …, 2022 - Wiley Online Library
Cell metabolism heavily relies on the redox reactions that inevitably generate reactive
oxygen species (ROS). It is now well established that ROS fluctuations near basal levels …
oxygen species (ROS). It is now well established that ROS fluctuations near basal levels …
Roles of N-methyl-D-aspartate receptors (NMDARs) in epilepsy
S Chen, D Xu, L Fan, Z Fang, X Wang… - Frontiers in Molecular …, 2022 - frontiersin.org
Epilepsy is one of the most common neurological disorders characterized by recurrent
seizures. The mechanism of epilepsy remains unclear and previous studies suggest that N …
seizures. The mechanism of epilepsy remains unclear and previous studies suggest that N …
L-serine synthesis via the phosphorylated pathway in humans
L-serine is a nonessential amino acid in eukaryotic cells, used for protein synthesis and in
producing phosphoglycerides, glycerides, sphingolipids, phosphatidylserine, and …
producing phosphoglycerides, glycerides, sphingolipids, phosphatidylserine, and …
The role of D-amino acids in Alzheimer's disease
L Piubelli, G Murtas, V Rabattoni… - Journal of Alzheimer's …, 2021 - content.iospress.com
Abstract Alzheimer's disease (AD), the main cause of dementia worldwide, is characterized
by a complex and multifactorial etiology. In large part, excitatory neurotransmission in the …
by a complex and multifactorial etiology. In large part, excitatory neurotransmission in the …
[HTML][HTML] Homeostasis of serine enantiomers is disrupted in the post-mortem caudate putamen and cerebrospinal fluid of living Parkinson's disease patients
L-serine generated in astrocytes plays a pivotal role in modulating essential neurometabolic
processes, while its enantiomer, D-serine, specifically regulates NMDA receptor (NMDAR) …
processes, while its enantiomer, D-serine, specifically regulates NMDA receptor (NMDAR) …
Colorimetric quantification of sodium benzoate in food by using d-amino acid oxidase and 2D metal organic framework nanosheets mediated cascade enzyme …
H Zhang, H Yang, P Liu, X Qin, G Liu - Talanta, 2022 - Elsevier
A rapid colorimetric method for detecting sodium benzoate in food products was established
based on the d-amino acid oxidase (DAAO) and 2D metal organic framework (2D MOF) …
based on the d-amino acid oxidase (DAAO) and 2D metal organic framework (2D MOF) …
Reactive oxygen species as a double‐edged sword: The role of oxidative enzymes in antitumor therapy
E Rosini, L Pollegioni - BioFactors, 2022 - Wiley Online Library
A number of approaches have been developed over the years to manage cancer, such as
chemotherapy using low‐molecular‐mass molecules and radiotherapy. Here, enzymes can …
chemotherapy using low‐molecular‐mass molecules and radiotherapy. Here, enzymes can …