[HTML][HTML] Colonic drug delivery: Formulating the next generation of colon-targeted therapeutics
Colonic drug delivery can facilitate access to unique therapeutic targets and has the
potential to enhance drug bioavailability whilst reducing off-target effects. Delivering drugs to …
potential to enhance drug bioavailability whilst reducing off-target effects. Delivering drugs to …
A review on curcumin colon-targeted oral drug delivery systems for the treatment of inflammatory bowel disease
Synthetic drugs and monoclonal antibodies are the typical treatments to combat
inflammatory bowel disease (IBD). However, side effects are present when these treatments …
inflammatory bowel disease (IBD). However, side effects are present when these treatments …
[HTML][HTML] Development of polymeric-based formulation as potential smart colonic drug delivery system
Conventional oral formulations are mainly absorbed in the small intestine. This limits their
use in the treatment of some diseases associated with the colon, where the drug has to act …
use in the treatment of some diseases associated with the colon, where the drug has to act …
Strategies and opportunities of micro/nano delivery systems for targeted therapy of ulcerative colitis: Focus on underlying mechanisms and future perspectives
Z Liu, H Liu, J Cheng, H Wang, Y Yang, J Ye… - Chinese Chemical …, 2024 - Elsevier
Ulcerative colitis (UC) is a common progressive inflammatory disease whose incidence has
increased rapidly in recent years, and can develop into colorectal cancer in severe cases …
increased rapidly in recent years, and can develop into colorectal cancer in severe cases …
[HTML][HTML] Comparison of 5-ASA layered or matrix pellets coated with a combination of ethylcellulose and eudragits L and s in the treatment of ulcerative colitis in rats
The aim of this study was to evaluate and optimize the combination of time and pH-
dependent polymers as a single coating for the design of the colon-specific drug delivery …
dependent polymers as a single coating for the design of the colon-specific drug delivery …
Formulation and development of curcumin–piperine-loaded S-SNEDDS for the treatment of alzheimer's disease
Curcumin (CUR) and piperine (PIP) are very well-known phytochemicals that claimed to
have many health benefits and have been widely used in foods and traditional medicines …
have many health benefits and have been widely used in foods and traditional medicines …
Nano-curcumin formulations for targeted therapy of colorectal cancer
Colorectal cancer (CRC) is the third most common cause of cancer death in men and
women. Chemotherapeutic drugs such as 5-fluorouracil (5-FU), irinotecan, and oxaliplatin …
women. Chemotherapeutic drugs such as 5-fluorouracil (5-FU), irinotecan, and oxaliplatin …
[HTML][HTML] Combination of time-dependent polymer and inulin as a coating for sustained delivery of budesonide pellets aimed for use in IBD treatment
Crohn's disease and ulcerative colitis, both forms of inflammatory bowel disease (IBD), are
prevalent conditions. Budesonide, a medication widely recommended as a first-line …
prevalent conditions. Budesonide, a medication widely recommended as a first-line …
pH/enzyme dual sensitive Gegenqinlian pellets coated with Bletilla striata polysaccharide membranes for the treatment of ulcerative colitis
LF Sun, MM Li, Y Chen, WJ Lu, Q Zhang… - Colloids and Surfaces B …, 2023 - Elsevier
Abstract Gegen Qinlian Decoction, derived from Zhang Zhongjing's Treatise on Typhoid
Fever, has been widely used in the treatment of various common diseases, frequently …
Fever, has been widely used in the treatment of various common diseases, frequently …
Colon delivery of resveratrol for the treatment of inflammatory bowel disease
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal
tract (GIT) that can affect any part of the GIT. The side effects of chemical drugs in the …
tract (GIT) that can affect any part of the GIT. The side effects of chemical drugs in the …