Asthma is a chronic disease of the airways, which affects more than 350 million people
worldwide. It is the most common chronic disease in children, affecting at least 30 million …

Interleukin-5 (IL-5) exerts a central pathogenic role in differentiation, recruitment, survival,
and degranulation of eosinophils. Indeed, during the last years, significant advances have …

This review will describe the structure and function of the eosinophil. The roles of several
relevant cell surface molecules and receptors will be discussed. We will also explore the …

Despite being the second least represented granulocyte subpopulation in the circulating
blood, eosinophils are receiving a growing interest from the scientific community, due to their …

Studies on neonicotinoid (NEO) exposure in pregnant women and fetuses are scarce, and
transplacental transfer of these insecticides is unknown. In this study, parent NEOs (p-NEOs) …

Rhinitis is a heterogeneous condition that has been associated with inflammatory responses
as in allergic rhinitis but can also occur in the absence of inflammation such as in so‐called …

Eosinophils have been traditionally perceived as terminally differentiated cytotoxic effector
cells. Recent studies have profoundly altered this simplistic view of eosinophils and their …

Dendritic cells, macrophages and B cells are regarded as the classical antigen-presenting
cells of the immune system. However, in recent years, there has been a rapid increase in the …

Eosinophils are bone marrow‐derived granulocytes and are found in low numbers in the
peripheral blood of healthy subjects. In type 2 inflammatory diseases, eosinopoiesis in the …

Experimental and clinical data strongly support a role for the eosinophil in the pathogenesis
of asthma, allergic and parasitic diseases, and hypereosinophilic syndromes, in addition to …