Chronic lung diseases represent a major public health problem with only limited therapeutic
options. An important unmet need is to identify compounds and drugs that target key …

Although chronic obstructive pulmonary disease (COPD) risk is strongly influenced by
cigarette smoking, genetic factors are also important determinants of COPD. In addition to …

Background Multimorbidities greatly increase the global health burdens, but the landscapes
of their genetic risks have not been systematically investigated. Methods We used the …

Many studies have proved that the pathogenesis of the chronic obstructive pulmonary
disease (COPD) and lung cancer is related, and may cause and affect each other to a …

Chronic obstructive pulmonary disease (COPD) is a debilitating inflammatory lung disease
and the third leading cause of death worldwide (1). COPD is characterized by three major …

Iron is essential for many biological processes, however, too much or too little iron can result
in a wide variety of pathological consequences, depending on the organ system, tissue or …

Chronic obstructive pulmonary disease (COPD) and lung cancer are major lung diseases
affecting millions worldwide. Both diseases have links to cigarette smoking and exert a …

Background There is growing evidence that chronic obstructive pulmonary disease (COPD)
can increase the risk of lung cancer, which poses a serious threat to treatment and …

Background Single nucleotide polymorphism (SNP) is a genetic variation that occurs when a
single nucleotide base in the DNA sequence varies between individuals and is present in at …

Background Chronic obstructive pulmonary disease (COPD) is one of the leading causes of
death in the world. Not much is known regarding the influence of non-smoking-related risk …