Body-weight supported locomotor training (BWST) promotes recovery of load-bearing
stepping in lower mammals, but its efficacy in individuals with a spinal cord injury (SCI) is …

Introduction Millions of people worldwide suffer with spasticity related to irreversible damage
to the brain or spinal cord. Typical antecedent events include stroke, traumatic brain injury …

Muscle spasms are common in chronic spinal cord injury (SCI), posing challenges to
rehabilitation and daily activities. Pharmacological management of spasms mostly targets …

Motoneurons provide the only conduit for motor commands to reach muscles. For many
years, motoneurons were in fact considered to be little more than passive “wires”. Systematic …

Spinal cord injury (SCI) often disrupts the integrity of afferent (sensory) axons projecting
through the spinal cord dorsal columns to the brain. Examinations of ascending sensory …

Correct operation of neuronal networks depends on the interplay between synaptic
excitation and inhibition processes leading to a dynamic state termed balanced network. In …

Key points Cutaneous reflexes were tested to examine the neuronal mechanisms
contributing to muscle spasms in humans with chronic spinal cord injury (SCI). Specifically …

Introduction The gate control theory of pain was the starting point of the development of
spinal cord stimulation (SCS). We describe the indications for the treatment in pain …

Objective: To develop a large animal model of spinal cord injury (SCI), for use in
translational studies of spinal cord stimulation (SCS) in the treatment of spasticity. We seek …

Trunk motor control is crucial for postural stability and propulsion after low thoracic spinal
cord injury (SCI) in animals and humans. Robotic rehabilitation aimed at trunk shows …